September 29 2015 Issue
1) Hemorrhagic stroke following use of the synthetic marijuana "spice" and 2) Topic of the month: Updates in tele-neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Justin Sattin interviews Dr. David Rose about his paper on hemorrhagic stroke following use of the synthetic marijuana "spice." Dr. Sarah Wesley is reading our e-Pearl of the week about Hirayama disease. In the next part of the podcast Dr. Andy Southerland interviews Dr. Jennifer Majersik about the topic of tele-neurology quality measures. The participants had nothing to disclose except Drs. Rose, Wesley, Southerland and Majersik.Dr. Rose serves as an editorial board member of Neurohospitalist Journal and serves on the Speakers' bureau of Boehringer Ingelheim.Dr. Wesley serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Southerland serves as Podcast Deputy Editor for Neurology®; serves as Clinical Research Advisor for Totier Technologies, Inc.Dr. Majersik receives research support from the NIH.
CONCLUSIONS: Inflammatory markers like NLR, LMR and CAR on admission were associated with increased risks of 30-day mortality and 90-day poor outcome in patients with critically ill stroke. Especially, high NLR is independently associated with 90-day poor outcome. PMID: 32486607 [PubMed - as supplied by publisher]
(NIH/National Institute of Neurological Disorders and Stroke) In a nationwide study, NIH funded researchers found that the presence of abnormal bundles of brittle blood vessels in the brain or spinal cord, called cavernous angiomas (CA), are linked to the composition of a person's gut bacteria. Also known as cerebral cavernous malformations, these lesions which contain slow moving or stagnant blood, can often cause hemorrhagic strokes, seizures, or headaches.
Palato-pharyngo-laryngeal myoclonus, a variant of palatal myoclonus, is characterized by involuntary rhythmic movements of palatal, pharyngeal, and laryngeal muscles. Symptomatic palatal myoclonus is classical...
CONCLUSIONS: Patients with diabetes mellitus were vulnerable to hemorrhagic transformation, whereas those who underwent several attempts of thrombectomy were susceptible to isolated subarachnoid hemorrhage. Both hemorrhage types worsened the functional outcome. Treatment with the stent retriever was significantly associated with postprocedural isolated subarachnoid hemorrhage. PMID: 32475194 [PubMed - as supplied by publisher]
AbstractBackground and purposeRandomized controlled trials have demonstrated that mechanical thrombectomy (MT) could provide more benefit than standard medical care for acute ischemic stroke (AIS) patients due to emergent large vessel occlusion. However, most primary stroke centers (PSCs) are unable to perform MT, and MT can only be performed in comprehensive stroke centers (CSCs) with on-site interventional neuroradiologic services. Therefore, there is an ongoing debate regarding whether patients with suspected AIS should be directly admitted to CSCs or secondarily transferred to CSCs from PSCs. This meta-analysis was aim...
ConclusionThe neurological manifestations of the COVID-19 are varied and the data about this continue to evolve as the pandemic continues to progress.
The association between CHADS2 score and stroke has been confirmed in patients with atrial fibrillation. But the majority of cardiovascular events occurred primarily in population without atrial fibrillation. Therefore, we performed this cohort study to evaluate the association between baseline CHADS2 score and cardiovascular events in the population without atrial fibrillation. A total of 99,755 Chinese adults with complete baseline data were followed for up to 10 years. The primary outcomes were cardiovascular event (a composite endpoint of myocardial infarction, cerebral infarction and cerebral hemorrhage) and all-cause death.
This study aimed to investigate characteristics and outcomes of newly developed stroke in patients admitted to the non-neurological intensive care units (ICU-onset stroke, IOS).MethodsA consecutive series of adult patients who were admitted to the non-neurological ICU were included in this study. We compared neurological profiles, risk factors, and mortality rates between patients with IOS and those without IOS.ResultsOf 18,604 patients admitted to the ICU for non-neurological illness, 218 (1.2%) developed stroke (ischemic,n = 182; hemorrhagic,n = 36). The most common neurological presentation w...
(Medical University of South Carolina) Reperfusion therapy, the gold standard in stroke treatment, returns blood flow to the affected brain area and must be administered within four hours of stroke to minimize hemorrhage risk. Even with successful return of blood flow, full brain function recovery is rare. Medical University of South Carolina researchers have shown in a preclinical stroke model that adding a unique compound to reduce brain inflammation significantly improves cognitive recovery and extends the treatment window.
Conclusions: The Hua-Shan program provided the opportunity to maximize the benefits of contralateral seventh cervical nerve transfer.IMPLICATIONS FOR REHABILITATIONStandard rehabilitation plays key roles in the recovery process for patients undergoing contralateral seventh cervical nerve transfer.The Hua-Shan program targeting nerve regeneration, brain plasticity and group therapy further improved the benefits of patients undergoing contralateral seventh cervical nerve transfer. PMID: 32478582 [PubMed - as supplied by publisher]