Four new triterpenoid saponins isolated from Schefflera kwangsiensis and their inhibitory activities against FBPase1

Publication date: March 2016 Source:Phytochemistry Letters, Volume 15 Author(s): Yan Wang, Yan-Fei Liu, Chun-Lei Zhang, Dong Liang, Huan Luo, Zhi-You Hao, Ruo-Yun Chen, De-Quan Yu Four new triterpenoid saponins, schekwangsiensides H–K (1–4) were isolated from the aerial parts of Schefflera kwangsiensis, together with fifteen esters (5–19) of known saponins. The structures of these compounds were elucidated on the basis of spectroscopic data analysis and chemical evidence. Furthermore, in in vitro assays, compounds 3, 8, 17, and 18 exhibited weak inhibitory activities against fructose-1,6-bisphosphatase (FBPase1). Graphical abstract

Source: Phytochemistry Letters - January 22, 2016 Category: Chemistry Source Type: research