ACS Releases Long-term Care Guideline for Breast Cancer Survivors

By Stacy Simon The American Cancer Society and the American Society of Clinical Oncology have released a new Breast Cancer Survivorship Care Guideline to help breast cancer survivors and their primary care providers better manage their long-term care. The guideline was published December 7, 2015 in CA: A Cancer Journal for Clinicians, a journal of the American Cancer Society. It provides detailed recommendations for how and when to test for new or returning cancers, managing side effects, making healthy lifestyle changes, and coordinating care among primary care providers and specialists. The guideline is the third in a series of cancer survivorship guidelines developed by the American Cancer Society. The first two made recommendations for survivors of prostate cancer and survivors of colorectal cancer. The Society is developing survivorship care guidelines for other cancer types as well, based on the number of survivors and the severity of health problems survivors face. An estimated 3.1 million breast cancer survivors are living today in the United States. The average age at diagnosis is 61 years; therefore it is important that long-term survivorship care is managed in coordination with health problems associated with aging. Testing for cancer The most common treatment for breast cancer is surgery, often in combination with radiation, chemotherapy, and/or targeted therapy. After treatment, the new guidelines recommend that survivors get regular follow-up tests and physical ...
Source: American Cancer Society :: News and Features - Category: Cancer & Oncology Tags: Breast Cancer Coping with Cancer Source Type: news

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ConclusionsWalking posture can affect both psychological and physiological states. Applications of these findings may have implications for improving mental and physiological health.
Source: Journal of Behavior Therapy and Experimental Psychiatry - Category: Psychiatry Source Type: research
Authors: Lee HJ, Han YM, An JM, Kang EA, Park YJ, Cha JY, Hahm KB Abstract INTRODUCTION: Although inflammation is defensive and healing process that maintains organ homeostasis, unresolved inflammation can lead to diseases. Polyunsaturated fatty acids (PUFAs), especially n-6 PUFAs abundant in Western diet, are precursors of pro-inflammatory mediators, whereas n-3 PUFAs possess anti-inflammatory properties. Therefore, interest in the cancer-preventive effect of n-3 PUFAs is increasing. Areas covered: We have observed significant reductions of gastrointestinal (GI) tumorigenesis in the Fat-1 transgenic mouse as evide...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
Authors: Jones RL, Le Cesne A, Ibrahim T, Garcia Del Muro X, Menge F Abstract INTRODUCTION: Health-related quality of life (HRQoL) is a patient-reported outcome that addresses patients' perceptions of symptoms across physical, emotional, cognitive and social domains. As HRQoL is currently rarely measured outside clinical trials in oncology, it must be inferred from patients' everyday performance during treatment. To gain insight into the HRQoL of advanced STS patients receiving palliative treatment in clinical practice, three case studies of patients treated with trabectedin are examined. Areas covered: The patient...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
was established in 2004 and consents patients in Wales, UK with a known or suspected cancer diagnosis to donate biosamples for future research. The resource is open access to all researchers working in cancer research, regardless of geographic location or employment sector. To December 2017, just over 13,500 patients have donated samples across a variety of tumour types. Tumour and adjacent normal tissue and blood samples are routinely collected, stored and processed to standardised protocols. Bespoke collections for unique samples such as urine or ascites are also available. Pathology data, clinical data including treatm...
Source: Open Journal of Bioresources - Category: Biotechnology Source Type: research
Authors: Czemerska M, Robak T, Wierzbowska A Abstract INTRODUCTION: Acute myeloid leukemia (AML) remains a poor prognosis hematological malignancy. The introduction of aggressive chemotherapy with allogeneic stem cell transplantation has resulted in improved clinical outcomes in younger patients. However, the treatment results in unfit elderly AML population remain disappointing. New strategies should be introduced to improve the prognosis in this group of patients. Areas covered: This review presents and discusses the mechanism of action, safety and efficacy of sapacitabine in AML patients. Expert opinion: Sapacit...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
(Reuters Health) - Postmenopausal women who experience problems like vaginal dryness, painful intercourse or urinary incontinence may want to see a gynecologist instead of a primary care provider for help, a recent study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Publication date: Available online 17 September 2018Source: Life SciencesAuthor(s): Lingli Liang, Yuan-Xiang TaoAbstractAimsHistone acetylation and deacetylation are two histone posttranslational modifications that are usually controlled by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Although HATs or HDACs Inhibitors could relieve pain hypersensitivities in chronic pain animal models, it is not clear on the expression of global histone acetylation in the dorsal root ganglion (DRG) or spinal dorsal horn in chronic pain conditions.Main methodsA spinal nerve ligation (SNL)-induced neuropathic pain mode...
Source: Life Sciences - Category: Biology Source Type: research
ConclusionsIn children with abdominal pain and/or diarrhea, increased ESR, CRP and decreased albumin combined with a high fecal calprotectin level yields additional diagnostic value in screening potential patients with Crohn’s disease. As far as differentiation of ulcerative colitis is concerned, low additional diagnostic value was found when high fecal calprotectin was combined with albumin.
Source: Advances in Medical Sciences - Category: Biomedical Science Source Type: research
Publication date: 20 December 2018Source: Sensors and Actuators B: Chemical, Volume 277Author(s): Xiangge Tian, Zhenhao Tian, Yan Wang, Jie Hou, Lei Feng, Liang Song, Jingnan Cui, Xiaokui Huo, Xinyu Zhao, Dayong Zhou, Chao Wang, Chengpeng Sun, Jing Ning, Xiaochi MaAbstractCisplatin is a widely used anti-cancer drug in clinic, while many cancer cells gradually exhibited serious cisplatin resistance recently, which resulted in reducing its clinical effects. Glutathione transferases (GSTs) as an extensive expressed metabolic enzyme in human, plays a significant role in the metabolism of cisplatin. Thus, sensitively and accura...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Publication date: 20 December 2018Source: Sensors and Actuators B: Chemical, Volume 277Author(s): Tianlin Wang, Zhanhui Tao, Yanlong Lyu, Pengcheng Qian, Yunfei Li, Xiaodong Lin, Shuo Wang, Yaqing LiuAbstractHighly sensitive detection of cysteine is critical for early warning and diagnosis of cysteine-associated diseases. For the first time, herein, a reusable and ratiometric fluorescent biosensor with simple operation was developed for sensitive and rapid detection of Cys on the basis of configuration transformation of guanine-rich DNA (G-DNA). The sensing system is quite simple and consisted of G-DNA and Ag+ with NMM (N-...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
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