Antifungal sesquiterpenoids from Chloranthus japonicus

Publication date: March 2016 Source:Phytochemistry Letters, Volume 15 Author(s): Xu-Hong Li, Huan Yan, Wei Ni, Xu-Jie Qin, Qing Zhao, Zhi-Qin Ji, Hai-Yang Liu Two new eudesmane-type sesquiterpenoids, chlojaponols A (1) and B (2), and four new lindenane-type sesquiterpenoid lactones, chlojaponilactones F-I (3–6), along with six known analogues were isolated from whole plants of Chloranthus japonicus. The structures of new compounds were established based on analyses of spectroscopic data including HR-MS, 1D and 2D NMR. The antifungal activities of some of the compounds were tested and compound 5 showed 82.61% inhibition to Sclerotinia sclerotiorumat the concentration of 50 μg/mL. Graphical abstract

Source: Phytochemistry Letters - January 21, 2016 Category: Chemistry Source Type: research