Inconsistency in the detection of phytotoxic effects: A test with Acacia dealbata extracts using two different methods

Publication date: March 2016 Source:Phytochemistry Letters, Volume 15 Author(s): Paula Lorenzo, Jonatan Reboredo-Durán, Luís Múñoz, Luís González, Helena Freitas, Susana Rodríguez-Echeverría The phytotoxic activity of novel natural compounds is generally evaluated by the bioassay-directed fractionation procedure conducted with bioassays on model species. Two different methodologies to dissolve the examined compounds, using either organic solvents and water, or dimethyl sulfoxide (DMSO) and buffered medium, are commonly used in these bioassays. However, whether the bioactivity of tested compounds is the same under those different conditions remains unexplored. To elucidate this, we designed a study to compare the activity of chemical compounds extracted from the allelopathic Acacia dealbata using different solvents. Natural compounds from flowers, leaves and bark were fractionated with hexane, ethyl acetate and water and bioassayed using either these solvents or a common DMSO-buffer medium for the three fractions. The effect of these compounds on the germination and seedling growth of Lactuca sativa was subsequently tested using a common bioassay design. The type of dissolving method had a significant effect on the bioactivity of A. dealbata compounds. In general, phytotoxic activity is increased by DMSO-Buffer Bioassays. A higher number of phytotoxic effects of hexane and ethyl acetate compounds were also found i...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research

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