Epigenetic inactivation of FAT4 contributes to gastric field cancerization

Conclusions FAT4 was methylation-silenced in GCs. Its methylation in gastric mucosae was associated with H. pylori infection and likely contributed to epigenetic field cancerization.

http://link.springer.com/10.1007/s10120-016-0593-5

Source: Gastric Cancer - January 20, 2016 Category: Gastroenterology Source Type: research