A Single EBUS-TBNA Procedure Can Support a Large Panel of Immunohistochemical Stains, Specific Diagnostic Subtyping, and Multiple Gene Analyses in the Majority of Non-Small Cell Lung Cancer Cases
Targeted therapies for pulmonary adenocarcinoma (ACA) necessitate specific subtyping and molecular testing of non-small cell lung carcinomas (NSCLC). However, endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has decreased the tissue available for these assessments. While EBUS-TBNA specimens have previously been reported to, successfully subtype NSCLC, allow immunohistochemistry (IHC), and support molecular diagnostics, no studies have documented the extent to which all objectives are possible in a single sample.
Source: Human Pathology - Category: Pathology Authors: Lisa M. Rooper, Olga Nikolskaia, Jamal Carter, Yi Ning, Ming-Tseh Lin, Zahra Maleki Source Type: research
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