Two patients in hospital in Scotland after contracting SWINE FLU

The patients, who have been diagnosed with the H1N1 strain of influenza, are being kept under observation at Wishaw General Hospital in North Lanarkshire, hospital officials confirmed today.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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AbstractInfluenza A viruses evolve rapidly to escape host immunity. In swine, this viral evolution has resulted in the emergence of multiple H1 and H3 influenza A virus (IAV) lineages in the United States (US) pig populations. The heterologous prime-boost vaccination strategy is a promising way to deal with diverse IAV infection in multiple animal models. However, whether or not this vaccination strategy is applicable to US swine to impart immunity against infection from North American strains of IAV is still unknown. We performed a vaccination-challenge study to evaluate the protective efficacy of using multivalent inacti...
Source: Veterinary Research - Category: Veterinary Research Source Type: research
TWiV reviews a new H1N1 swine influenza virus from China with pandemic potential, Ad5 vectored SARS-CoV-2 oral vaccine candidate, Operation Warp Speed vaccine candidates, FDA guidance on vaccine approval, and answer listener email. Click arrow to playDownload TWiV 634 (72 MB .mp3, 120 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology adenovirus COVID-19 FDA vaccine guidance Operation Warp Speed SARS-CoV-2 viral viruses Source Type: blogs
A new study warns that the strain of H1N1, common on China ’s pig farms since 2016, should be “urgently” controlled to avoid another pandemic.
Source: NYT Health - Category: Consumer Health News Authors: Tags: China Pigs Swine Influenza Proceedings of the National Academy of Sciences Source Type: news
Pandemic influenza A viruses can emerge from swine, an intermediate host that supports adaptation of human-preferred receptor-binding specificity by the hemagglutinin (HA) surface antigen. Other HA traits necessary for pandemic potential are poorly understood. For swine influenza viruses isolated in 2009 –2016, gamma-clade viruses had less stable HA proteins (activation pH 5.5–5.9) than pandemic clade (pH 5.0–5.5). Gamma-clade viruses replicated to higher levels in mammalian cells than pandemic clade. In ferrets, a model for human adaptation, a relatively stable HA protein (pH 5.5–5.6) was n ecessar...
Source: eLife - Category: Biomedical Science Tags: Microbiology and Infectious Disease Source Type: research
Conclusions: The speed of the emergency responses to H1N1 was faster than COVID-19, which might be an important influential factor for slowing down the arrival of the peak time at the beginning of the epidemic. Although COVID-19 in China is coming to an end, the government should improve the public health emergency system, in order to control the spread of the epidemic and lessen the adverse social effects in possible future outbreaks.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Read Fast Facts from CNN about the H1N1 influenza virus, also known as swine flu. There was a global outbreak which lasted from 2009 to 2010.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Nai-Huei Wu Pigs play an important role in the interspecies transmission of influenza A viruses (IAV). The porcine airway epithelium contains binding sites for both swine/human IAV (α2,6-linked sialic acids) and avian IAV (α2,3-linked sialic acids) and therefore is suited for adaptation of viruses from other species as suggested by the “mixing vessel theory”. Here, we applied well-differentiated swine airway epithelial cells to find out whether efficient infection by avian IAV requires prior adaption. Furthermore, we analyzed the influence of the sialic acid-binding activity an...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Publication date: Available online 19 May 2020Source: Veterinary MicrobiologyAuthor(s): Bao-Yang Ruan, Yun Yao, Shuai-Yong Wang, Xiao-Qian Gong, Xiao-Min Liu, Qi Wang, Ling-Xue Yu, Shi-Qiang Zhu, Juan Wang, Tong-Ling Shan, Yan-Jun Zhou, Wu Tong, Hao Zheng, Guo-Xin Li, Fei Gao, Ning Kong, Hai Yu, Guang-Zhi Tong
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
ez Sanvicente Sánchez-Betancourt Influenza, a zoonosis caused by various influenza A virus subtypes, affects a wide range of species, including humans. Pig cells express both sialyl-α-2,3-Gal and sialyl-α-2,6-Gal receptors, which make them susceptible to infection by avian and human viruses, respectively. To date, it is not known whether wild pigs in Mexico are affected by influenza virus subtypes, nor whether this would make them a potential risk of influenza transmission to humans. In this work, 61 hogs from two municipalities in Campeche, Mexico, were sampled. Hemagglutination inhibi...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Thomas A. FireyAmong the criticisms President Trump has received over his handling of COVID-19, one is that he ’s playing politics with disaster aid. TheDenver Post recently charged that he “is treating life‐​saving medical equipment as emoluments he can dole out as favors to loyalists.” Michigan Gov.Gretchen Whitmer has claimed that “vendors are being told not to send stuff here to Michigan.” Trump himself has said the governors “have to treat us well also” in order to get what they need.So far, evidence of actual favoritism is mixed. A Washington Post review of federal d...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
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