Annals of Neurology: Volume 79, Number 1, January 2016

ON THE COVER: Tau PET study from a 70 year‐old individual with a diagnosis of Mild Cognitive Impairment due to Alzheimer's disease, on the basis of a history of progressive memory impairment and elevated brain amyloid. Coronal PET image with the tau tracer 18F T807 (also known as AV1451; superimposed on MRI) shows high binding in red, localized in temporal neocortex, most prominently in inferior temporal gyrus bilaterally, with extension into middle and superior temporal gyri. The pattern of 18F T807 cortical binding is consistent with neurofibrillary tangle stage III/IV of Braak and Braak. For more information, see the article by Johnson et al. (pages 110–119).

Source: Annals of Neurology - January 19, 2016 Category: Neurology Tags: Cover Image Source Type: research