Make the Diagnosis: What Lies Beneath These Crusted Hands?

(MedPage Today) -- Case Findings: A 53-year-old man with a history of alcoholism presented with erosions on his hands. He said that they had started as vesicles, but now some of them had crusted. He had also noticed some hypertrichosis on his temples, along with redness of his face, which he thought was unusual. What is your diagnosis?
Source: MedPage Today Dermatology - Category: Dermatology Source Type: news

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CONCLUSIONS: Combining BTX-A injections for sialorrhea with multilevel intramuscular BTX-A injections (with or without alcohol) appears to be safe and effective and allows treatment of patients for both conditions simultaneously. PMID: 31227667 [PubMed - as supplied by publisher]
Source: Journal of Pediatric Rehabilitation Medicine - Category: Rehabilitation Tags: J Pediatr Rehabil Med Source Type: research
This study examines patterns and correlates of e-cigarette use frequency in a novel national sample. Methods: Data were from 36,277 US adults interviewed between 2012 and 2013 for the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III). Sociodemographic characteristics, other tobacco/drug use, and psychiatric disorders were compared by e-cigarette use status (i.e. current [past-month], past, never) and e-cigarette use frequency (i.e. infrequent [≤3 days/month], moderate [1-6 days/week], daily). Multinomial logistic regression models compared correlates of e-cigarette use...
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
Conclusion: The concomitant use of nicotine and areca indicates that betel quid addiction includes a significant component of nicotine dependence. However, the additional activities of areca, including the muscarinic effects of arecoline, indicate that potential cessation therapies should optimally address other factors as well. PMID: 31220988 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
Conclusions: Findings underscore the critical role of acculturation and alcohol-related problems in cannabis use frequency and have relevant implications for preventive efforts addressing cannabis use among Latinas at risk of an AEP. PMID: 31220980 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
Tens of thousands of Instagram followers can't be wrong: Curiosity about the sober life is trending. Scientists say cutting out alcohol can improve your sleep and blood pressure, and help your liver.(Image credit: Julia Robinson for NPR)
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news
In this study, we developed and tested various antimicrobial polyvinyl alcohol (PVA)/tea polyphenol (TP) composite films intended to extend the shelf life of packaged strawberries. Each PVA/TP film with volumetric ratios of 10/0, 9/1, 8/2, 7/3, 6/4 and 5/5 was prepared using tap-casting methods and characterized with respect to its infrared spectrum, tensile strength, oxygen permeability, water solubility, biodegradation, and antimicrobial properties. The effects of the various composite films were subsequently evaluated based on the fruit's weight loss, decay rate, firmness, pH, titratable acidity, and soluble solids. The...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
In this study, the protective activity of Acacia senegal gum and its macromolecular fractions (HIC–F1, HIC–F2 and HIC–F3), separated according to their hydrophobicity, towards the precipitation of iron hexacyanoferrate salts and polyphenols in hydro-alcoholic solutions are reported. AGPs prevent the colloidal instability of both iron hexacyanoferrate salts and polyphenols in “model” hydro-alcoholic solutions and young red wine with a good correlation between results obtained on both systems. This result strengthens the use of iron hexacyanoferrate salts (hydro-alcoholic – mineral test) f...
Source: Food Hydrocolloids - Category: Food Science Source Type: research
Publication date: 15 November 2019Source: Food Chemistry, Volume 298Author(s): Will Kew, Ian Goodall, Dušan UhrínAbstractScotch Whisky has been analysed as a complex mixture in its raw form using high resolution Nuclear Magnetic Resonance (NMR) and previously developed water and ethanol suppression techniques. This has allowed for the positive identification of 25 compounds in Scotch Whisky by means of comparison to reference standards, spike-in experiments, and advanced 1D and 2D NMR experiments. Quantification of compounds was hindered by signal overlap, though peak alignment strategies were largely success...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 21 June 2019Source: Journal of BiotechnologyAuthor(s): Chen Zhang, Ying Zang, Peng Liu, Zhaojuan Zheng, Jia OuyangAbstract4-Coumarate: CoA ligase (4CL) is an important branch point directing metabolites to flavonoid or monolignol pathways in plants. It plays a vital role in the biosynthesis of plant nature products in microbes. Herein, Ptr4CL4, Ptr4CL5 and Ptr4CL7 from Populus trichocarpa were cloned and expressed in Escherichia coli. Two recombinant proteins Ptr4CL4 and Ptr4CL5 showed distinct activities for different substrates. The Ptr4CL4, not previously reported, showed the hi...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
In this study, we prepared Zn/Al-Cl LDH with different Zn:Al molar ratios for immobilization of the lipase from Pseudomonas cepacia. The best values for activity retention (188%), immobilization efficiency (96%) and hydrolytic activity in organic medium (279 U g-1) were obtained with a molar ratio of Zn:Al of 4:1, a protein loading of 162 mg g-1 and Tris-HCl buffer (10 mmol L-1, pH 7.5) as the solvent for preparing the lipase solution. The immobilized lipase keeps its activity when stored at 4 °C during 30 days. The immobilized lipase gave a conversion of 50% in 1 h for the kinetic re...
Source: Enzyme and Microbial Technology - Category: Biotechnology Source Type: research
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