Non-alcoholic Wernicke Encephalopathy

This 18-year-old man with a history of plasmablastic lymphoma and secondary hemophagocytic lymphohistiocytosis presented status post bone marrow transplant with acute onset of increasing somnolence, right hemiparesis, and seizures. A bedside electroencephalography showed normal findings. T2-weighted fluid-attenuated inversion recovery and diffusion-weighted magnetic resonance imaging (MRI) revealed symmetric signal hyperintensity and restricted diffusion involving the bilateral medial thalami, mammillary bodies, hypothalamus, tectum, left perirolandic cortex, and bilateral medial frontal cortex (Figure).

Source: Pediatric Neurology - December 18, 2015 Category: Neurology Authors: Daniel A. Lyons, Luke L. Linscott, Darcy A. Krueger Tags: Visual Diagnosis Source Type: research