Study points to new biological mechanisms, treatment paradigm for kidney disease
Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure. New research led by Icahn School of Medicine at Mount Sinai investigators has uncovered abnormal molecular signaling pathways from disease initiation to irreversible kidney damage, kidney failure, and death. Results from their preclinical and human research are published online in the Journal of Clinical Investigation.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Urology / Nephrology Source Type: news