The Next Big Short

Mike Burry, the hedge fund manager featured in the movie The Big Short, anticipated the housing crash by reading loan documents. Similarly, those in the food and agriculture arena predict a massive shift in farming practices by studying the inimical effects of the widely used weedkiller, RoundUp®. Glyphosate (the main ingredient in RoundUp®) has been under fire lately for its effects on human health. In March 2015, 17 experts from 11 countries analyzed the effect of glyphosate at the International Agency for Research on Cancer (IARC) and deemed it a probable carcinogen. It's important to note that the USA uses 20% of the world's RoundUp® yet only comprises 5% of the world's population. As a result of the World Health Organisation's (WHO) announcement that glyphosate is a probable carcinogen, many law firms are opening class action suits against billion dollar chemical industry leaders.(1,2,3,4,5) Matthew Philips, a Las Vegas attorney, is suing Monsanto for false advertising. The filing papers state, "Defendant makes the claim that Roundup®, the world's most popular weedkiller, works by targeting an enzyme supposedly found only in plants, but not in people. And this is blatantly false." The reason it's false is that, as a registered antibiotic, glyphosate kills essential gut bacteria. Without these bacteria, humans cannot manufacture enzymes that produce seratonin and dopamine, the feel-good chemicals. Glyphosate also disrupts our ability to absorb es...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: Available online 17 October 2018Source: Respiratory Medicine Case ReportsAuthor(s): Saad Habib, Lazer Ezriel Leifer, Mohammed Azam, Abdul Hasan Siddiqui, Kartikeya Rajdev, Michel ChalhoubAbstractGiant Cell Carcinoma of the lung, a subtype of Sarcomatoid lung cancer is a poorly differentiated Non-Small-Cell Lung Cancer. GCCL has exceptionally aggressive characteristics, and its prognosis is much poorer than any other NSCLCs. Herein, we present a rare case of Giant Cell Carcinoma of lung treated successfully with surgical resection and adjuvant vinorelbine and cisplatin.A 48-year-old African American man wi...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Authors: Fontana J, Zima M, Vetvicka V Abstract Numerous conditions, including cancer, diabetes, aging, and atherosclerosis, are thought to be associated with oxidative stress. Oxidative stress is defined as a persistent imbalance between oxidation and antioxidation, resulting in the damage of cellular macromolecules and is often considered to be involved in wide variety of human diseases. However, the current literature is very heterogeneous making it rather difficult to draw general conclusions. Often, different biomarkers have been used in different health problems. In addition, individual biomarkers are often m...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Authors: Mosaad YM, Metwally SS, Farag RE, Lotfy ZF, AbdelTwab HE Abstract BACKGROUND: Inconsistent results were reported on the association of TLRs polymorphisms with the risk of HCV infection and HCV-related diseases. OBJECTIVE: to assess the relation between TLR3 rs3775290, TLR7 rs17900 and TLR9 rs352140 SNPs and chronic HCV in the Egyptian cohort and to study their relation to interferon response. METHODS: TLR3 rs3775290, TLR7 rs179008 and TLR9 rs352140 gene polymorphisms were typed by RFLP for 100 patients with chronic HCV and 25 with HCC in addition to 100 healthy controls. RESULTS: A significant ...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
In conclusion, the Vγ9Vδ2 T cells activated by cancer cell lysate showed APC characteristics, and this may greatly increase interest in investigating their therapeutic potential in hematologic malignancies. Abbreviations: CML: chronic myeloid leukemia; APC: antigen-presenting cell; TCR: T cell receptor; MHC: major histocompatibility complex; N-BPs: nitrogen-containing bisphosphonates; IPP: isopentenyl pyrophosphate; PBMC: peripheral blood mononuclear cells; NKG2D: natural killer receptor group 2, member D; TRAIL: tumor necrosis factor-related apoptosis-inducing ligand. PMID: 30321079 [PubMed - as supplied by publisher]
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Publication date: Available online 16 October 2018Source: NeuroImage: ClinicalAuthor(s): Xing Liu, Yiming Li, Zenghui Qian, Zhiyan Sun, Kaibin Xu, Kai Wang, Shuai Liu, Xing Fan, Shaowu Li, Zhong Zhang, Tao Jiang, Yinyan WangAbstractObjectiveThe aim of this study was to develop a radiomics signature for prediction of progression-free survival (PFS) in lower-grade gliomas and to investigate the genetic background behind the radiomics signature.MethodsIn this retrospective study, training (n = 216) and validation (n = 84) cohorts were collected from the Chinese Glioma Genome Atlas and the Cancer Genome Atlas, respecti...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
ConclusionWe describe the use of a processing pipeline to aid clinicians and researchers engaged in deep brain stimulation work to correlate and visualize the intraoperative recording data with the post-operative DBS trajectory.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Authors: Papadia A, Gasparri ML, Wang J, Radan AP, Mueller MD Abstract The risk of lymph nodal metastases in endometrial cancer varies greatly according to the characteristics of the primary tumor. Surgical staging with a systematic lymphadenectomy in endometrial cancer is debated since three decades. On one hand, it provides important pathological information on the spread of the tumor allowing for an appropriate decision making on adjuvant treatment but on the other side it is characterized by a non negligible short and long term morbidity. In the past decades, various efforts have been made in the attempt to app...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
CONCLUSIONS: This systematic review confirms the importance of HE4 in the diagnosis of epithelial ovarian cancer and its promising role in endometrial cancer (endometrioid hystology). PMID: 30318876 [PubMed - as supplied by publisher]
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
CONCLUSIONS: Management of pregnant women with cancer should be performed in specialized cancer centers and all cases should be discussed with a multidisciplinary approach. In the present review, we discuss the current recommendations for the management of pregnancies complicated by cancer and neonatal outcomes. PMID: 30318875 [PubMed - as supplied by publisher]
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
HOW TO live longer: Eating a healthy and balanced diet is one of the ways proven to increase life expectancy, but what exactly should you be eating? Nuts have been found to improve heart health and prevent serious conditions like type 2 diabetes and bowel cancer. So which ones should you be eating?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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