ALung Technologies raises $10.8 million

Artificial lung-like device developer ALung Technologies raised $10.8 million in a new round of debt financing according to an SEC filing posted this week. The money already raised in the round comes from 63 unnamed investors, according to the SEC filing. Pittsburgh-based ALung’s Hemolung device is an extracorporeal carbon dioxide removal system that works by removing carbon dioxide and delivering oxygen directly to a patient’s blood via a small catheter inserted into the jugular or femoral vein. The company said that the remaining $1.2 million it looks to raise includes notes that are to be issued to Equinox Securities Melvin Pirchesky as part of a commission, according to the filing. Early last month, ALung Technologies said its Hemolung RAS extracorporeal carbon dioxide removal device was selected for use in the world’s 1st pivotal trial of ECCO2R technology used to treat patients with acute respiratory failure. The U.K.’s National Institute for Health Research will supply $3.1 million (GBP £2.1 million) in funding for the 1,120 patient Rest trial, which looks to examine the effect of protective ventilation with veno-venous lung assist devices during respiratory failure. The trial will be jointly led by Queen’s University and Belfast Health and Social Services Trust, the company said. The post ALung Technologies raises $10.8 million appeared first on MassDevice.
Source: Mass Device - Category: Medical Equipment Authors: Tags: Blog Source Type: news

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Conditions:   Lung Diseases;   Lung Neoplasm Intervention:   Procedure: Endobronchial Ultrasound Sponsors:   St. Joseph's Healthcare Hamilton;   NeuralSeg Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Lung Transplantation;   Chronic Lung Allograft Dysfunction;   Rejection Lung Transplant Intervention:   Other: Early detection of CLAD by Lung Clearance Index (LCI) Sponsor:   University of Zurich Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Lung Diseases;   Lung Neoplasm Intervention:   Procedure: Endobronchial Ultrasound Sponsors:   St. Joseph's Healthcare Hamilton;   NeuralSeg Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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rin Nicolas Glaichenhaus Joel Guigay Marius Ilié Bernard Mari Charles-Hugo Marquette Véronique Paquis-Flucklinger Frédéric Prate Pierre Saintigny Barbara Seitz-Polsky Taycir Skhiri Ellen Van Obberghen-Schilling Emmanuel Van Obberghen Laurent Yvan-Charvet It is generally accepted that carcinogenesis and aging are two biological processes, which are known to be associated. Notably, the frequency of certain cancers (including lung cancer), increases significantly with the age of patients and there is now a wealth of data showing that multiple mechanisms leading to mali...
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PMID: 30785776 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
Cystic fibrosis liver disease (CFLD) remains the third leading cause of death in patients with cystic fibrosis. Although most patients with CFLD present in childhood, recent studies suggest a second wave of liver disease in adulthood. There are no clear guidelines for diagnosing CFLD. Treatment options for CFLD remain limited, and while UDCA is widely used, its long-term benefit is unclear. Those who develop hepatic decompensation or uncontrolled variceal bleeding may benefit from liver transplant, either alone, or in combination with lung transplant.
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CONCLUSION: Our results suggest that ESS is associated with a reduction in the frequency of antibiotic utilization for respiratory tract infections in lung transplant recipients with CF. A prospective study is needed to investigate these relationships further. PMID: 30781973 [PubMed - as supplied by publisher]
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