Cerebral β-Amyloid Angiopathy Is Associated with Earlier Dementia Onset in Alzheimer's Disease.

CONCLUSIONS: Our results suggest that CAA contributes to changes in early AD pathogenesis. This supports the idea that vascular change and neuritic plaque deposition are not just parallel processes but reflect additive pathological cascades that influence the course of clinical AD manifestation. Further inquiry into the role of CAA and its contribution to early cognitive change in AD is suggested. PMID: 26756746 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26756746?dopt=Abstract

Source: Neuro-Degenerative Diseases - January 13, 2016 Category: Neurology Authors: Vidoni ED, Yeh HW, Morris JK, Newell KL, Alqahtani A, Burns NC, Burns JM, Billinger SA Tags: Neurodegener Dis Source Type: research