The anxiolytic-like activity of a novel N-cycloalkyl-N-benzoylpiperazine derivative.

CONCLUSIONS: The anxiolytic-like properties of N-bicyclo-[3.1.0]hexyl derivative (9) in the four plate test are mediated by the opioid system. The results obtained make this compound a promising lead structure for further development of anxiolytic drugs. PMID: 26721353 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/26721353?dopt=Abstract

Source: Pharmacological Reports - January 13, 2016 Category: Drugs & Pharmacology Authors: Strub DJ, Sałat K, Librowski T, Lochyński S, Gaweł M, Podkowa A Tags: Pharmacol Rep Source Type: research