In vivo protective effect of betulinic acid on dexamethasone induced thymocyte apoptosis by reducing oxidative stress.

CONCLUSIONS: These findings reveal a protective capability of BA against Dex-induced cell death by reducing oxidative stress via mitochondrial mediated signal pathway which could be the potential mechanism underlying BA-elicited immunomodulation.
PMID: 26721359 [PubMed - in process]

Source: Pharmacological Reports - January 13, 2016 Category: Drugs & Pharmacology Authors: Yi J, Zhu R, Wu J, Wu J, Xia W, Zhu L, Jiang W, Xiang S, Tan Z Tags: Pharmacol Rep Source Type: research