Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma

Conclusions This study suggests that in a murine model of chronic asthma, long-term azithromycin treatment ameliorates not only airway inflammation but also airway remodeling by influencing on neutrophilc-related mediators, BRP-39 and MAPK/NF-κB signal pathways. Macrolide therapy might be an effective adjuvant therapy in a chronic, severe asthma with remodeling airway.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research