Kounis syndrome induced by cefditoren pivoxil

Kounis syndrome (KS) encompasses acute coronary syndromes such as coronary spasm, acute myocardial infarction, and stent thrombosis, concurrent with allergic, anaphylactic or anaphylactoid insults [1]. Despite allergy to beta-lactams is the first cause of drug allergy worldwide, only a scarce number of cephalosporins hitherto have been identified as a cause of KS, such as cefuroxime [2–5], ceftriaxone [6–8], cephradine [2], cefoperazone [4], cefoxitin [2,4], and cefazolin [2,9]. To our knowledge, we illustrate the first case report of KS due to cefditoren pivoxil (CP).

Source: International Journal of Cardiology - January 9, 2016 Category: Cardiology Authors: J. Barbarroja-Escudero, M.J. Sánchez-González, D. Antolín-Amérigo, M. Rodríguez-Rodríguez, P. Salinas, A. Fernandez-Ortiz, M. Alvarez-Mon Tags: Correspondence Source Type: research