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Cardiotoxic Cancer Therapy in Kids Tied to Early Heart DiseaseCardiotoxic Cancer Therapy in Kids Tied to Early Heart Disease

Screen for cardiac disease for all adult survivors of childhood cancers who were exposed to anthracyclines or radiotherapy to fields that included the heart, researchers recommend. Heartwire from Medscape
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Source Type: news

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continues to be a national health problem, linked to a number of chronic medical conditions, such as diabetes and heart disease, and even to some types of cancer. The estimated annual health care costs of obesity-related illness are a staggering $190.2 billion or nearly 21% of annual medical spending in the United States. Childhood obesity alone is responsible for $14 billion in direct medical costs. Obesity has risen a full 34% since 1960, while morbid obesity is up sixfold. If the prevalence continues on the current trend, it is estimated that by 2030 almost half of the world ’s population will be overweight or obese.
Source: Orthopedic Clinics of North America - Category: Orthopaedics Authors: Tags: Preface Source Type: research
(Reuters Health) - Adult survivors of childhood cancer have a greater risk of heart disease and develop risk factors like high blood pressure and elevated cholesterol earlier in life compared to the general population, a German study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
ConclusionsWe observed high excess long‐term mortality for all‐cause, renal failure, ischemic heart disease and heart failure mortality in African‐American and white American people with early‐onset insulin‐treated diabetes.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - Category: Endocrinology Authors: Tags: Research Article Source Type: research
In conclusion, most experimental data on immune changes with aging show a decline in many immune parameters when compared to young healthy subjects. The bulk of these changes is termed immunosenescence. Immunosenescence has been considered for some time as detrimental because it often leads to subclinical accumulation of pro-inflammatory factors and inflammaging. Together, immunosenescence and inflammaging are suggested to stand at the origin of most of the diseases of the elderly, such as infections, cancer, autoimmune disorders, and chronic inflammatory diseases. However, an increasing number of gerontologists have chall...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The long term poor health outcomes in people who have experienced multiple adverse events in childhood have been well documented since the original CDC-Kaiser study in the late 1990's. Those people who have experienced four or more adverse childhood experiences (ACE) are at significantly increased risk of chronic disease such as cancer, heart disease and diabetes as well as mental illness and health risk behaviours. The ACE pyramid is a model that describes the relationship between ACEs, disease and potentially early death.
Source: Paediatrics and Child Health - Category: Pediatrics Authors: Tags: Symposium: social paediatrics Source Type: research
Achieving ketosis by engaging in a very low-carbohydrate, high-fat lifestyle is an effective means of losing weight, breaking insulin and leptin resistance, reversing type 2 diabetes and fatty liver, reducing blood pressure, reversing the inflammation of visceral fat, and may even cause partial or total remission of selected cancers. So what’s the problem? The problem comes when people remain ketotic for extended periods. We know with confidence that long-term ketosis poses substantial risk for health complications because thousands of children have followed ketogenic diets over the years as a means of suppressing in...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Undoctored Wheat Belly Lifestyle Source Type: blogs
UCLA researchers have made new inroads into understanding germ cell tumors, a diverse and rare group of cancers that begin in germ cells — the cells that develop into sperm and eggs. The researchers developed a protocol to recreate germ cell tumor cells from stem cells and used the new model to study the genetics of the cancer.Their findings could point the way toward new drugs to treat germ cell tumors, which account for around 3 percent of all cases of childhood and adolescent cancer.The study, published in Stem Cell Research, was led by Amander Clark, a UCLA professor of molecular cell and developmental biology an...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
January 19, 2018It ’s notallbad news.When we set out to compile our annual list of global health issues to watch this year, it seemed like all bad news. And true, that ’s often what we deal with in global health—the problems that need tackling, the suffering we can help alleviate.But then stories and columns likethis one cheer us up. They remind us that no matter how complicated and frustrating our work may get, fighting back against poverty and inequality works.There are and always will be global health challenges to face. But there ’s boundless hope, too. And a field full of determined health work...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Source Type: news
Elizabeth Parrish of BioViva, you might recall, has made every effort to publicize the follistatin and telomerase gene therapy that she underwent. This is a strategy intended to accelerate progress; I suspect she was not the first, and that others were just more circumspect. The technology exists, it is not expensive in the grand scheme of things, and at the very least hundreds of people have the laboratory access and the knowledge to carry out such an operation. BioViva's efforts, and those of other ventures such as the Odin and Ascendance Biomedical illustrate the tension between desire for progress and desire for regula...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
In this study, we used the Clinical Practice Research Datalink (CPRD) to estimate clinically measured SBP and DBP trajectories for 20 years prior to death, for individuals dying at 60 years and older. Second, we compared the linear SBP trends for years 10 to 3 years before death in patients who died and age- and sex-matched controls who survived at least 9 years. These approaches aimed to separate age from end-of-life associations, and avoid healthy survivor biases. Twenty years before death, estimated mean SBPs increased with increasing age at death (60-69 years, 139.5 mm Hg; ≥90 years, 150.0 mm Hg). All age-at-...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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