Cardiotoxic Cancer Therapy in Kids Tied to Early Heart DiseaseCardiotoxic Cancer Therapy in Kids Tied to Early Heart Disease

Screen for cardiac disease for all adult survivors of childhood cancers who were exposed to anthracyclines or radiotherapy to fields that included the heart, researchers recommend. Heartwire from Medscape
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Source Type: news

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Gummy vitamins are increasingly popular—and not just for kids. By some estimates, adults now comprise up to 80% of the gummy vitamin market. “Pill fatigue” is one factor driving grownups toward gummies. If you have to take multiple supplements every day—and especially if you have problems swallowing capsules or tablets—gummies can make that chore easier (and tastier), finds a 2017 report from the AARP. But do gummy vitamins work the same as ordinary supplements? “It’s a lot harder to make a good gummy than it is to make a tablet or capsule,” says Dr. Tod Cooperman, president ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition Source Type: news
  Answer: No—unless you do it for more than a few months. After a few months, the upfront metabolic and weight benefits will begin to reverse and new health problems arise. We know this with confidence. I raise this question once again because more and more people are coming to me reporting problems. It may take months, even years, but the long-term consequences can be quite serious. Achieving ketosis by engaging in a very low-carbohydrate, high-fat lifestyle is—without a doubt—an effective means of losing weight, breaking insulin and leptin resistance, reversing type 2 diabetes and fatty liver, redu...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: ketones bowel flora ketogenic ketotic undoctored wheat belly Source Type: blogs
This study shows the incidence of cancer associated with obesity has been rising dramatically in groups of individuals born in more recent decades,” said MD Anderson Cancer Center’s Dr. George Chang, who was not associated with the analysis. However, Chang warns against overgeneralizing on the basis of an epidemiological study. “The study was not set up to establish causation,” Chang said. “We know there are many factors that are associated with both obesity and cancer, such as lack of exercise and poor diet. How much each of those factors contribute to cancer is less clear.” Obesity is ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Cancer CNN Millennials Source Type: news
In this study, we examined the benefits of early-onset, lifelong AET on predictors of health, inflammation, and cancer incidence in a naturally aging mouse model. Lifelong, voluntary wheel-running (O-AET; 26-month-old) prevented age-related declines in aerobic fitness and motor coordination vs. age-matched, sedentary controls (O-SED). AET also provided partial protection against sarcopenia, dynapenia, testicular atrophy, and overall organ pathology, hence augmenting the 'physiologic reserve' of lifelong runners. Systemic inflammation, as evidenced by a chronic elevation in 17 of 18 pro- and anti-inflammatory cytokin...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging. Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ConclusionsOur work showed that several circulating miRNAs are differentially represented in overweight/low-grade obesity children and adolescents. Although causal pathways cannot be firmly inferred, it is conceivable that circulating miRNAs may be new biomarkers of early childhood obesity.Trial registrationISRCTN,ISRCTN62310987. Registered 23/02/2018 - Retrospectively registered.
Source: Genes and Nutrition - Category: Nutrition Source Type: research
Grains are seeds of grasses. They, along with the Kentucky bluegrass and rye grass in your lawn, are plants from the family Poaceae, the grasses of the earth. Grasses are so ubiquitous and prolific that creatures have evolved that are able to survive by consuming them as their main source of food.  Ruminants such as cows, goats, sheep, giraffes, gazelle, and antelopes are able to digest grasses because they have undergone extensive evolutionary adaptation over millions of years that allow them to subsist on grasses as a food supply. For instance, ruminants: Grow teeth continuously to compensate for the wear...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates Gliadin gluten grain grain-free grains Inflammation wheat belly Source Type: blogs
In this study, we found that TNF-α resulted in an impairment of autophagic flux in microglia. Concomitantly, an increase of M1 marker expression and reduction of M2 marker expression were observed in TNF-α challenged microglia. Upregulation of autophagy via serum deprivation or pharmacologic activators (rapamycin and resveratrol) promoted microglia polarization toward M2 phenotype, as evidenced by suppressed M1 and elevated M2 gene expression, while inhibition of autophagy with 3-MA or Atg5 siRNA consistently aggravated the M1 polarization induced by TNF-α. Moreover, Atg5 knockdown alone was suffic...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: The incidence, age-distribution, locations and underlying disorders agree with published findings in pediatric populations. In our study, 87% of the children with VTE had either an identifiable acquired or genetic risk factor or a combination of both. Of those with a genetic risk factor, 13% had a recurrent VTE during the study period which indicates an even higher cumulative risk during childhood which emphasizes the need to consider prophylaxis in situations with increased risk of VTE. However, of those with recurrent VTE, no frequent acquired risk factor was identified.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - Category: Hematology Authors: Tags: 331. Pathophysiology of Thrombosis: Poster III Source Type: research
This study's researchers approached all people turning 85 in 2006 in two cities in the UK for participation. At the beginning of the study in 2006-2007, there were 722 participants, 60 percent of whom were women. The participants provided researchers with information about what they ate every day, their body weight and height measurements, their overall health assessment (including any level of disability), and their medical records. The researchers learned that more than one-quarter (28 percent) of very old adults had protein intakes below the recommended dietary allowance. The researchers noted that older adults w...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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