Treatment of Osteonecrosis in Children and Adolescents with Acute Lymphoblastic Leukemia

Conclusions No standard of care exists for treatment of ALL-associated ON. While considerable practice variation exists, surgical intervention appears relatively safe. Teaser Osteonecrosis (ON) is a well-recognized complication of therapy for children with acute lymphoblastic leukemia (ALL). In this cohort of newly diagnosed ALL patients followed for up to five years, 2.33% incidence of ON was identified by ICD-9 code. Overall, 22.7% underwent some form of surgical management with considerable hospital variation in both the rate and type of surgical intervention.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research