Digital breast tomosynthesis (DBT): a review of the evidence for use as a screening tool.

Digital breast tomosynthesis (DBT): a review of the evidence for use as a screening tool. Clin Radiol. 2016 Feb;71(2):141-50 Authors: Gilbert FJ, Tucker L, Young KC Abstract Breast screening with full-field digital mammography (FFDM) fails to detect 15-30% of cancers. This figure is higher for women with dense breasts. A new tomographic technique in mammography has been developed - digital breast tomosynthesis (DBT) - which allows images to be viewed in sections through the breast and has the potential to improve cancer detection rates. Results from retrospective reading studies comparing DBT with FFDM have been largely favourable with improvement in sensitivity and specificity. Increases in diagnostic accuracy have been reported as being independent of breast density; however there are mixed reports regarding the detection of microcalcification. Prospective screening studies using DBT with FFDM have demonstrated increased rates in cancer detection compared with FFDM alone. A reduction in false-positive recall rates has also been shown. Screening with the addition of DBT would approximately double radiation dose; however a simulated FFDM image can be generated from a DBT scan. The combination of simulated FFDM images and DBT is being evaluated within several studies and some positive results have been published. Interval cancer rates for the UK National Health Service Breast Screening Programme (NHSBSP) demonstrate the limited sensit...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Clin Radiol Source Type: research