Propranolol's impact on cognitive performance in post-traumatic stress disorder - Mahabir M, Ashbaugh AR, Saumier D, Tremblay J.

BACKGROUND: Propranolol has effectively diminished fear-based emotional memories in posttraumatic stress disorder (PTSD) and this effect has been attributed to traumatic memory reconsolidation blockade. However, propranolol may also exert cognitive effects...
Source: SafetyLit - Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

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Individuals with post-traumatic stress disorder avoid trauma-related stimuli and exhibit blunted hypothalamic–pituitary–adrenal axis response at the time of trauma. Our laboratory uses predator odor (i.e. bobcat urine) stress to divide adult Wistar rats into groups that exhibit high (avoiders) or low (nonavoiders) avoidance of a predator odor-paired context, modeling the fact that not all humans exposed to traumatic events develop psychiatric conditions. Male avoiders exhibit lower body weight gain after stress, as well as extinction-resistant avoidance that persists after a second stress exposure. These animal...
Source: Behavioural Pharmacology - Category: Drugs & Pharmacology Tags: REVIEW ARTICLES Source Type: research
Despite being banned in the 1970s,1 psychedelics are experiencing a cultural renaissance, with growing evidence suggesting compounds like psilocybin, MDMA, LSD, and ketamine may be effective therapies in controlled medical settings.2 Researchers have observed particular benefits for psychedelics in treatment of refractory depression, anxiety, substance addiction (tobacco/alcohol), PTSD, and in palliative care for patients facing terminal cancer.3,4
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Source Type: research
This study examined the longitudinal effects of co-occurring psychosocial concerns, or syndemics, on HIV-positive sexual minority men's likelihood of engaging in serodiscordant condomless anal sex (CAS), a health behavior with implications for personal and public health. Participants included 390 HIV-positive sexual minority men from two prior secondary prevention trials. Over the course of the 1-year data collection period (up to 5 observations per participant), participants completed self-report measures of CAS, as well as six syndemic factors: post-traumatic stress disorder, childhood sexual abuse, depression, anxiety, ...
Source: Archives of Sexual Behavior - Category: Psychiatry & Psychology Authors: Tags: Arch Sex Behav Source Type: research
You might have seen it in your neighborhood health store, your local spa or your corner coffee shop. CBD, aka cannabidiol, is getting mixed into cocktails, lotions and drinks. But what is CBD, exactly? Does it have real health benefits? Is it even safe? To get a better understanding of the compound, TIME spoke to two scientists on the cutting edge of CBD research: Dr. Esther Blessing, an associate professor of psychiatry at New York University, and Margaret Haney, professor of neurobiology at Columbia University Medical Center and director of the university’s Marijuana Research Laboratory. Blessing and Haney agree th...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime Research Source Type: news
Abstract Patients entering an inpatient psychiatry program (N = 406) with co-occurring mental health and substance use disorders reported on their social support networks (source, type) at treatment intake, and completed symptom measures at baseline and 3-, 9-, and 15-month follow-ups (77%). Longitudinal growth models found aspects of participants' support networks were associated with specific symptoms over time. Less family support (i.e., more conflict) was the most consistent predictor of mental health and substance use outcomes and was associated with greater psychiatric, depression, Post Traumat...
Source: Community Mental Health Journal - Category: Psychiatry Authors: Tags: Community Ment Health J Source Type: research
OBJECTIVE:: The study compared delay of treatment for posttraumatic stress disorder (PTSD), major depressive disorder, and alcohol use disorder among post-9/11 veterans versus pre-9/11 veterans and civilians. METHODS:: The 2012-2013 National Epidem...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
CONCLUSIONS:: Post-9/11 veterans were less likely to delay treatment for some common psychiatric conditions compared with pre-9/11 veterans or civilians, which may reflect efforts to engage recent veterans in mental health care. All groups exhibited low initiation of treatment for alcohol use disorder, highlighting the need for further engagement efforts. PMID: 30841842 [PubMed - as supplied by publisher]
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
OBJECTIVE: Posttraumatic stress disorder (PTSD) often co-occurs with substance use (SU). Although there has been independent research on subgroups of participants based on their PTSD or SU responses, rarely are PTSD-SU typologies examined consistent with a...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
CONCLUSIONS: Results provide construct validity support for three meaningful latent classes with unique relations with depression and RSDBs. These findings improve our understanding of heterogeneous PTSD-SU comorbidity patterns and highlight acknowledgment of such subtyping (subgrouping) in considering differential treatment options, treatment effectiveness, and resource allocation. PMID: 30838935 [PubMed - as supplied by publisher]
Source: Journal of Dual Diagnosis - Category: Addiction Tags: J Dual Diagn Source Type: research
CONCLUSION: Family assessments and therapeutic approaches are needed for OSYs with both PTSS and alcohol use problems. PMID: 30836738 [PubMed - as supplied by publisher]
Source: Psychiatry Investigation - Category: Psychiatry Tags: Psychiatry Investig Source Type: research
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