Statins up-regulate SmgGDS through {beta}1-integrin/Akt1 pathway in endothelial cells

Conclusion
These results indicate that statins selectively up-regulate SmgGDS in endothelial cells, for which the β1-integrin/Akt1 pathway may be involved, demonstrating the novel aspects of the pleiotropic effects of statins.

Source: Cardiovascular Research - December 28, 2015 Category: Cardiology Authors: Minami, T., Satoh, K., Nogi, M., Kudo, S., Miyata, S., Tanaka, S.-i., Shimokawa, H. Tags: Vascular Biology Source Type: research