Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy
Conclusion
Our study demonstrates that mTORC2 is implicated in maintaining contractile function of the pressure-overloaded male mouse heart.
Source: Cardiovascular Research - Category: Cardiology Authors: Shende, P., Xu, L., Morandi, C., Pentassuglia, L., Heim, P., Lebboukh, S., Berthonneche, C., Pedrazzini, T., Kaufmann, B. A., Hall, M. N., Rüegg, M. A., Brink, M. Tags: Cardiac biology and remodelling Source Type: research