Neuregulin-1 improves right ventricular function and attenuates experimental pulmonary arterial hypertension

Conclusion
rhNRG-1 treatment attenuates pulmonary arterial and RV remodelling, and dysfunction in a rat model of MCT-induced PAH and has direct anti-remodelling effects on the pressure-overloaded RV.

Source: Cardiovascular Research - December 28, 2015 Category: Cardiology Authors: Mendes-Ferreira, P., Maia-Rocha, C., Adao, R., Mendes, M. J., Santos-Ribeiro, D., Alves, B. S., Cerqueira, R. J., Castro-Chaves, P., Lourenco, A. P., De Keulenaer, G. W., Leite-Moreira, A. F., Bras-Silva, C. Tags: Integrative physiology and pathophysiology Source Type: research