Rexahn initiates Phase Ib clinical trial of RX-3117 for treatment of solid tumors
RX-3117 has broad spectrum anti-tumor activity against 80 different human cancer cell lines (including NSCLC, breast, ovarian, pancreas, colon, renal, brain, bladder, cervical) and efficacy in 12 different mouse xenograft models (including colorectal, non-small cell lung, pancreatic and renal cell carcinoma) superior to that of gemcitabine.01/10/2014
Authors: Turan AS, Ultee G, Van Geenen EJM, Siersema PD Abstract INTRODUCTION: The most commonly used treatment for advanced colorectal adenomas is endoscopic mucosal resection (EMR). The increased number of EMRs since the introduction of the screening program for colorectal cancer has resulted in an increase in EMR-related complications. This review summarizes the current knowledge for the use of clips for the treatment and prevention of complications after EMR. Areas covered: The historical development of clips is summarized and their properties are evaluated. An overview is presented of the evidence for therapeu...
Chem. Commun., 2019, Advance Article DOI: 10.1039/C9CC01506J, CommunicationYuan Ma, Quanbing Mou, Lijuan Zhu, Yue Su, Xin Jin, Jing Feng, Deyue Yan, Xinyuan Zhu, Chuan Zhang Polygemcitabine nanogels assembled from DNA-like polygemcitabine undergo rapid intracellular degradation to generate active gemcitabine derivatives for enhanced cancer therapy. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
AbstractObjectiveTo evaluate factors associated with use of patient navigation in a prostate cancer population and identify whether navigation is associated with prolonged time to care. Cancer patient navigation has been shown to improve access to cancer screening, diagnosis, and treatment, but little is known about patient navigation in prostate cancer care.MethodsAll men diagnosed with localized prostate cancer between 2009 and 2015 were abstracted from the MaineHealth multi-specialty tumor registry. Regression analyses controlling for patient-, disease-, and system-level factors evaluated characteristics ass...
ConclusionIn conclusion, this study illustrates that the application and benefits of HS on reducing GI rectal dose endpoints and toxicities during prostate cancer RT can be reliably replicated in a community setting similar to centres participating in the randomised trial under high quality assurance trial monitoring.
ConclusionThere is a need to enhance a constant patient –HCP dialogue, and both groups need to make a conscious effort in that direction. This would help in increasing patients’ awareness of risks, having better treatment choice and acceptance, and reducing side-effects.
(copied from reddit) Hey guys, So I wanted to follow up on a previous thread I started, which discussed some obstacles and hardships I faced as an undergrad, which included losing my mom to cancer over the course of 2 years. In short, this left me broken mentally, physically, and a scar on my academic career. My GPA was significantly impacted and it decreased incredibly through those years, however, the past 3... What to do next? Graduate and kind of lost right now
Publication date: August 2019Source: Journal of Functional Foods, Volume 59Author(s): Bernadetta Lis, Beata OlasAbstractSince ancient times, dandelion (Taraxacum officinale L.) has been consumed in various forms as a valuable source of nutrients, minerals and vitamins which can also have beneficial effects on various complex diseases. It is described as a nontoxic herb with exceptional biological activity. The aim of this review is to present the multidirectional activity of various dandelion products whose dietary intake may help to prevent, or reduce the risk of, the development of a range of diseases, including cancer, ...
Hello. It's been three years since I graduated from my undergrad university. I graduated with a 2.94 overall gpa and 2.0 science gpa. During college my mother was diagnosed with cancer and my father simultaneously lost his job. Along with these stressors and immature study habits, I just didn't place importance on school work. Since graduating, I have taken some post-bacc classes informally at a cc near my house. Made all A's in them. Then, I joined a one year masters program to gain a... Nontrad applicant chance me
LUNG cancer symptoms include having a cough that won ’t go away, chest pain, and difficulty breathing. But you could also be at risk of a tumour if you have any of these “unusual” signs. Should you speak to a doctor?
Authors: Grzelczyk WL, Wróbel-Roztropiński A, Szemraj J, Cybula M, Pietruszewska W, Zielińska-Kaźmierska B, Jozefowicz-Korczynska M Abstract Introduction: The aim of the study was to investigate the mRNA expression and protein levels of matrix metalloproteinases (MMP) 2 (MMP-2), 9 (MMP-9), 7 (MMP-7) and their tissue inhibitor TIMP-2 in patients with laryngeal squamous cell carcinoma and control subjects and additionally to evaluate a possible correlation with clinicopathological features. Material and methods: The expression levels of MMP-2, MMP-9, MMP-7, and TIMP-2 mRNA were detected by the real-time...
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