Behind the Headlines' Top Five of Top Fives 2015

In this study, researchers wanted to see why this is and if there could be any human applications.Researchers collected white blood cells from African and Asian elephants. They found that elephants have at least 20 copies of a gene called TP53. TP53 is known to encourage cell "suicide" when DNA is damaged, stopping any potential cancer in its tracks. In contrast, humans are thought to have only a single copy of the TP53 gene.Of course the big question – the elephant in the room, if you will – is how we can boost TP53 activity in humans to stimulate a similar protective effect. The simple answer is: we don't know. Yet. Researchers 'a step closer' to universal flu vaccineIt's just like buses. You wait years for a potential universal flu vaccine, then two come along at once. In August, two studies were published, both on the possibility of creating a "one-size jab" for flu.The flu virus is shaped like a ball, with many "spikes" sticking out of its surface made of a chemical called haemagglutinin. The "stem" part of this spike does not change as much as its tip or other parts of the virus, so both of these studies aimed to develop a vaccine that targeted the stem. Targeting these areas may help keep the vaccines effective, even if new strains come along.Both vaccines were able to protect mice against what would usually be a lethal dose of flu, and one vaccine reduced fever symptoms in monkeys.While the results were encouraging, ...
Source: NHS News Feed - Category: Consumer Health News Tags: QA articles Medical practice Special reports Source Type: news

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Publication date: 1 December 2018Source: Materials Science and Engineering: C, Volume 93Author(s): Anasuya Roy, Mangala Joshi, B.S. Butola, Sahil MalhotraAbstractWith increasing demand for novel and potent antimicrobial agents to combat cross-infections and infectious diseases, silver and copper based nanoparticles (NPs) deposited over supports such as montmorillonite (MMT) are playing a crucial role in shaping the current research scenario. Although materials based on Ag NP and Cu NP on MMT have been reported, its toxicological properties on human cell lines have not been accounted for. This paper reports a comparative st...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 20 August 2018Source: Biocybernetics and Biomedical EngineeringAuthor(s): R. Sumathi, M. Venkatesuslu, Sridhar P. Arjunan
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Mona Randolph, 82, of Missouri, is only one of three polio survivors left in the US that uses an iron lung machine, which is no longer made and leaves her with responsibility of repair and maintenance.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 20 August 2018Source: NeurocomputingAuthor(s): Junjie Zhang, Yong Xia, Haoyue Zeng, Yanning ZhangAbstractDetection of pulmonary nodules on chest CT is an essential step in the early diagnosis of lung cancer, which is critical for best patient care. In this paper, we propose an automated pulmonary nodule detection algorithm, denoted by NODULe, which jointly uses a conventional method for nodule detection and a deep learning model for genuine nodule identification. Specifically, we first use multi-scale Laplacian of Gaussian (LoG) filters and prior shape and size constraints to detect nodul...
Source: Neurocomputing - Category: Neuroscience Source Type: research
ConclusionLow PNI predicts poor survival in LC patients.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
CONCLUSIONS: This study shows that IHC with the tested antiserum increases the sensitivity of the diagnosis and may be recommended for routine use in EMB analyses of cardiac transplant patients with Chagas disease.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
CONCLUSIONS: The present study documents the occurrence of neurocryptococcosis, which is mainly caused by C. neoformans VNI, in Mato Grosso do Sul, Brazil, with probable autochthonous cases in the Brazilian Pantanal, the world ’ s largest tropical wetland, and a biome where cryptococcosis has not yet been explored.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Imogen Riddett, 22, from Windsor, is literally a life-saver after stem cells she donated helped stranger, Claire Daly, from Coventry, overcome leukaemia aged 30.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
This study investigated the associations between infants’ attention to emotional faces and infants’ and parents’ negative emotions in a community sample. Infants’ (N = 57, Mage = 14.26 months) fixations and pupil responses to fearful, sad, angry versus happy and neutral faces were measured with an eye-tracker. Mothers’ and fathers’ negative emotions (negative affect, depression, and anxiety), and infants’ negative temperament were measured with questionnaires. Infants looked longer at fearful than happy or neutral faces, while they showed less pupil dilation to fearful than to happ...
Source: Infant Behavior and Development - Category: Child Development Source Type: research
Publication date: Available online 20 August 2018Source: Antiviral ResearchAuthor(s): Hsu-Feng Chu, Chiao-Che Chen, David C. Moses, Yau-Hung Chen, Chao-Hsiung Lin, Ying-Chieh Tsai, Chi-Yuan ChouAbstractPorcine epidemic diarrhea virus (PEDV) is a coronavirus (CoV) discovered in the 1970s that infects the intestinal tract of pigs, resulting in diarrhea and vomiting. It can cause extreme dehydration and death in neonatal piglets. In Asia, modified live attenuated vaccines have been used to control PEDV infection in recent years. However, a new strain of PEDV that belongs to genogroup 2a appeared in the USA in 2013 and then qu...
Source: Antiviral Therapy - Category: Virology Source Type: research
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