Changes in bone mass during the perimenopausal transition in naturally menopausal cynomolgus monkeys

Conclusions: Unlike the ovariectomized monkey models that do not retain the perimenopausal transition, naturally menopausal monkeys elicit different patterns of bone loss during the transition—an abrupt decline in the trabecular metaphysis and a gradual decline in the cortical diaphysis. Naturally menopausal cynomolgus monkeys offer an alternative model for osteoporosis research for postmenopausal women.
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research