NSAIDs and InfertilityNSAIDs and Infertility

Can over-the-counter pain relievers cause infertility in women? Medscape Pharmacists
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Ask the Expert Source Type: news

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AbstractPurpose of ReviewOpioids are the cornerstone for pain treatment with significant recent increases in the number of prescriptions. Sexual dysfunction (SD) is a major side effect of opioid therapy. The goal of this review is to examine the current literature on the effects of opioids on male SD (erectile dysfunction [ED], hypogonadism, ejaculatory dysfunction) and infertility.Recent FindingsHigh prevalence of SD exists in men with opioid use as compared to the general population, with an abundance of evidence suggesting an association between opioid use and ED and hypogonadism. There appears to be a role for testoste...
Source: Current Sexual Health Reports - Category: Sexual Medicine Source Type: research
Uterine myomas are common benign monoclonal tumors with extremely low potential for malignancy. They are estimated to be present in up to 70% of women of reproductive age [1], with a higher incidence in obese women and those of African American descent, and when symptomatic, a frequent indication for gynecologic surgery. Although the presence of myomas may be associated with a plethora of symptoms including pelvic pain, abnormal uterine bleeding, infertility/subfertility, and adverse pregnancy outcomes [2], the vast majority of women with uterine fibroids are asymptomatic.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Perspective Source Type: research
Publication date: October 2018Source: Biomedicine &Pharmacotherapy, Volume 106Author(s): Awais Ullah Ihsan, Farhan Ullahp Khan, Puregmaa Khongorzul, Khalil Ali Ahmad, Muhammad Naveed, Sufia Yasmeen, Yanfang Cao, Abdoh Taleb, Richinandan Maiti, Fahad Akhter, Xiaoqian Liao, Xue Li, Yijie Cheng, Hidayat Ullah Khan, Khurshid Alam, Xiaohui ZhouAbstractOxidative stress (OS) is a result of the imbalance between reactive oxygen species (ROS) and antioxidants in the body that can cause tissue damage. Oxidative stress has a significant involvement in the pathogenesis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) ...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
​BY GREGORY TAYLOR, DO, &JACKLYN MCPARLANE​, DOA 31-year-old woman with a significant medical history for one ectopic pregnancy and five spontaneous abortions presented with abdominal pain and vaginal bleeding. Her symptoms started abruptly two days earlier, and the pain was located in the right lower quadrant, which had become diffuse and she described as sharp. She was also experiencing nausea, vomiting, and vaginal bleeding.She stated she had been spotting for five days and soaking up to four pads a day. Her last menstrual period was two months before, and a home pregnancy test was positive. Her presentation was...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
ConclusionModerate-to-severe endometriosis was more common in women with East or South East Asian ethnicity in our tertiary referral center. This could be explained by East/South East Asians with minimal-mild disease being less likely to seek care, or genetic/environmental differences that increase the risk of more severe disease amongst East/South East Asians.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionsUtility of oral diclofenac potassium one hour before HSG combined with cervical lidocaine 5% cream significantly alleviate the induced pain during and 30 min after the HSG procedure.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
ConclusionUtility of oral HBB 30 min before HSG has no benefit in alleviating the induced pain during and 30 min after the HSG procedure.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
Publication date: March 2018Source: Arab Journal of Urology, Volume 16, Issue 1Author(s): Scott D. Lundy, Edmund S. SabaneghAbstractDespite being first described two thousand years ago, the varicocele remains a controversial multifaceted disease process with numerous biological consequences including infertility, hypogonadism, and chronic orchidalgia. The underlying mechanisms remain poorly understood and likely include hypoxia, oxidative stress, hyperthermia, anatomical aberrations, and genetics as primary components. Despite a high prevalence amongst asymptomatic fertile men, varicoceles paradoxically also represent the ...
Source: Arab Journal of Urology - Category: Urology & Nephrology Source Type: research
Publication date: August 2018Source: Gynecologic Oncology Reports, Volume 25Author(s): Lisa N. Abaid, John S. Cupp, Miles Chang, Steven R. Beanes, Bram H. GoldsteinAbstractEndometriosis is a condition wherein an ectopic layer of endometrial tissue arises in an extra-uterine location, often effecting significant pelvic pain and infertility. While very uncommon, there have been reported cases of endometriosis undergoing malignant transformation, frequently involving the ovaries and seldom in extra-gonadal regions. We recount a case depicting a 63 year-old woman who presented with an apparent inguinal hernia in 2017; she wa...
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
We report the case of a 28-year-old nulliparous female with unexplained infertility who underwent freeze-all vaginal oocyte retrieval. Twenty-one days later she presented with vaginal bleeding (similar to menstruation) and right lower-quadrant pain. The results of ultrasound scanning and a laboratory work-up were consistent with an ectopic pregnancy. She underwent laparoscopic right salpingectomy for a tubal ectopic pregnancy. We recommend sexual abstinence during assisted reproduction to lower the risk of multiple pregnancy and especially of heterotopic pregnancy.
Source: Case Reports in Womens Health - Category: OBGYN Source Type: research
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