NSAIDs and InfertilityNSAIDs and Infertility

Can over-the-counter pain relievers cause infertility in women? Medscape Pharmacists
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Ask the Expert Source Type: news

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I am still not able to cope up with negative pregnancy test. I just wished that the test still comes positive. My good looking embryos do not like to settle in my good looking endometrium lining. I wish that I could know what these beautiful embryos wants more from me? Why all these medicines,efforts, patience, care, precautions and prayers for having a baby is not paying off. What else can we do to fulfill our dream to have a baby ?Crying is also not helping. After getting result, I spent entire day in reading positive ivf stories on internet I know that in this journey nobody get success immediately, every couple have th...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Authors: Zheng W, Cao L, Xu Z, Ma Y, Liang X Abstract Endometriosis is caused by the growth or infiltration of endometrial tissues outside of the endometrium and myometrium. Symptoms include pain and infertility. Surgery and hormonal therapy are widely used in Western medicine for the treatment of endometriosis; however, the side effects associated with this practice include disease recurrence and menopause, which can severely influence quality of life. Angiogenesis is the main biological mechanism underlying the development of endometriosis. Numerous natural products and Chinese medicines with potent anti-angiogen...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
AbstractBackgroundSurgical sperm retrieval, requiring local anesthetic injection, is the most frequent surgical procedure in male infertility. However, needle phobia is common and may contribute to negative experiences or refusal of procedures employing needle injection.ObjectivesThe aim of this study was to compare the acceptability, safety, and efficacy of needle ‐free jet anesthetic technique (MadaJet) with conventional needle injection for surgical sperm retrievals in patients with azoospermia.Materials and methodsThis single ‐blind randomized controlled trial (RCT) was included of 59 participants who underwent sur...
Source: Andrology - Category: Urology & Nephrology Authors: Tags: Original Article Source Type: research
Publication date: Available online 3 November 2018Source: Best Practice &Research Clinical Endocrinology &MetabolismAuthor(s): Dominique de Ziegler, Paul Pirtea, Marie Carbonnel, Marine Poulain, Ettore Cicinelli, Carlo Bulletti, Konstantinos Kostaras, George Kontopoulos, David Keefe, Jean Marc AyoubiAbstractEndometriosis – a disease causing pain and infertility – is encountered in nearly 50% of infertile women. While medical treatment is effective on pain and recurrence of symptoms after surgical excision, it is of no help for treating infertility for which the only options considered are surgery and AR...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
The objective of this study was to demonstrate a markedly enlarged isthmocele, that resulted in the miscarriage of a 12-week IVF twin pregnancy.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
The objective of this study is to study effect of laparoscopy surgery vs dienogest in reducing pain and effect on infertility associated with endometriosis.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
Objective: To demonstrate the laparoscopic evaluation and management of a patient with a complex urogenital anomaly presenting with pain, infertility, and use of her urethra for intercourse.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
Objective: Caesarean scar defect, or isthmocele, is a reservoir type pouch on the anterior wall of the uterine isthmus caused by inappropriate healing of the lower segment incision after caesarean section. The incidence of caesarean scar defects is reported to be as high as 84%, and is increasing due to the rising rates of caesarean sections worldwide. Caesarean scar defects may be asymptomatic, or cause a number of gynaecologic and obstetric sequealae, including abnormal bleeding, pelvic pain, infertility and ectopic scar pregnancy.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
​BY GREGORY TAYLOR, DO, &FRANK SCHELL, DOA 30-year-old woman presented to the ED complaining of pelvic pain. She said she felt an acute onset of sharp lower right pelvic pain during intercourse two days earlier. The pain continued to worsen, becoming diffuse. She was also experiencing nausea, vomiting, malaise, anorexia, and vaginal spotting. She had no history or concern for sexually transmitted disease, and had no fever or vaginal discharge. She had had a previous Cesarean section and bilateral tubal ligation.Her vital signs were a heart rate of 110 bpm, a respiratory rate of 25 bpm, a blood pressure of 113/88 mm H...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Abstract Endometriosis causes severe chronic pelvic pain and infertility. We have recently reported that niclosamide treatment reduces growth and progression of endometriosis-like lesions and inflammatory signaling (NFĸB and STAT3) in a mouse model. In the present study, we examined further inhibitory mechanisms by which niclosamide affects endometriotic lesions using an endometriotic epithelial cell line, 12Z, and macrophages differentiated from a monocytic THP-1 cell line. Niclosamide dose dependently reduced 12Z viability, reduced STAT3 and NFĸB activity, and increased both cleaved caspase-3 and cleaved PARP....
Source: Biology of Reproduction - Category: Reproduction Medicine Authors: Tags: Biol Reprod Source Type: research
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