Four women given pioneering womb transplants impregnated via IVF

Swedish medical team hoping for world first as women born without uterus or who lost it to cancer get embryo transfersFour of nine women given pioneering womb transplants in Sweden have now also had embryos transferred, the pioneering Swedish doctor treating them has said.Dr Mats Brannstrom, professor of obstetrics and gynaecology at Gothenburg University, said his team had embarked on a programme of embryo transfer for the women, who were either born without a womb or lost it as a result of cancer. All have ovaries so were able to produce eggs that were fertilised using IVF.Brannstrom predicted that three or four of the nine women might succeed in giving birth, which would be a world first. Other womb transplants have taken place in Saudi Arabia and Turkey but no recipients have yet managed to have a child. A pregnancy was achieved in Turkey, but it failed after two months."We have already begun transferring embryos into four of the women and plan to make attempts with the others when they are ready," said Brannstrom. He would not say whether any of the women were pregnant at the moment. In a study published last week, the team said that there were "mild rejection episodes" in four women who received donated wombs. Two patients had to have the uterus removed because of complications.Brannstrom's technique is controversial because he is accepting wombs donated by living women, who are relatives or friends of his patients. Elsewhere, wombs from dead donors ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: The Guardian Family Embryos IVF Biology Fertility problems World news Health Pregnancy & wellbeing Parents and parenting Society Europe Women Sweden Cancer Life and style Organ donation Science Source Type: news

Related Links:

In conclusion, the NR5A orphan nuclear receptors are nonredundant factors that are crucial regulators of a panoply of biological processes, across multiple reproductive tissues. PMID: 30810078 [PubMed - in process]
Source: Physiological Reviews - Category: Physiology Authors: Tags: Physiol Rev Source Type: research
Cancer treatment — and cancer itself — can threaten fertility. This is a tremendously important survivorship issue for many people. As an oncologist, I’m often asked questions about preserving fertility during cancer treatment. If this issue affects you, here is an overview of key options. When should you talk to your cancer team about fertility? Future children may not be foremost on your mind when you are diagnosed with cancer. Soon afterward, though, it’s worth talking to your doctor about fertility issues, if this is important to you now or might one day become important. Your doctor can explain...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Cancer Fertility Infertility Source Type: blogs
On an afternoon in November, a couple hosted a birthday party for their 1-year-old son. As family and friends gathered around the child to sing “Happy Birthday,” his parents addressed a milestone that reached well beyond the room. “It was emotional,” recalls the mother. “It took a lot more than a nine-month pregnancy to get him, and we wouldn’t be where we are without everyone’s support.” Many parents will tell you their child is miraculous. But the mere existence of this particular boy, who just a month earlier had taken his first steps, brings the miracle somehow closer to ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized fertility Research Source Type: news
The world’s first baby born by a uterus transplant from a deceased donor is healthy and nearing her first birthday, according to a new case study published Tuesday in the Lancet. Uterus transplants have become more common in recent years, resulting in 11 live births around the world. But all of the other successful deliveries so far have been made possible by living donors — often women who opt to donate their uterus to a close friend or family member without one. The birth resulting from the case detailed in the Lancet, which took place at Brazil’s Hospital das Clínicas last December, is both the first...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized fertility healthytime Source Type: news
Conclusions: Isolated distal DVT cases made up only a small percentage of all diagnosed incident CAT events for all cancer types analyzed, with the 2-year cumulative incidence ranging from 0.5% - 2.0% for stage 4 patients. Subsequent rVTE events in these patients were principally PE or p-DVT (73%). D-DVT was not a significant predictor of rVTE. A diagnosis of incident d-DVT was strongly associated with worse survival, and for most cancers, survival was similar among patients with an incident p-DVT or PE.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - Category: Hematology Authors: Tags: 332. Antithrombotic Therapy: Poster II Source Type: research
ConclusionCurettage for miscarriage or undesired pregnancy is not exempt from complications (as hemorrhage, simple perforation, or infection) Intrauterine fallopian tube incarceration is uncommon but can affect fertility. This diagnosis is important to avoid destruction of the fimbriae, necrosis of the tube and also to reduce the risk for ectopic pregnancy.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Most woman are worried about the possible risks and complications of doing IVF treatment, but part of the problem is the many myths and misconceptions which plague IVF . Thus, it is clear that IVF doesn't increase the risk of birth defects and it won't cause breast cancer or ovarian cancer, but lots of websites continue to disseminate this misinformation.However, as with any other treatment, there are potential complications and this is why selecting a good IVF doctor is so important. One of the possible medical risks is that of ovarian hyper-stimulation syndrome ( OHSS), but in a well-managed clinic, this risk should...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Abstract Follicle stimulating hormone (FSH) is a well characterized gonadotropin that controls primarily development and functions of ovarian follicles in mammalian species. FSH binds to a specific G protein-coupled receptor (FSHR) belonging to the glycoprotein hormone receptor family that plays an essential role in reproduction. Although the primary location of FSHR is in the gonads (mainly in ovarian follicles), FSHR protein and/or mRNA have also been detected in extragonadal female reproductive tissues including embryo, placenta, endometrium, cervix, ovarian cancer tissues, and/or endometriotic lesions in sever...
Source: Acta Histochemica - Category: Biochemistry Authors: Tags: Acta Histochem Source Type: research
Authors: Brăila AD, Krastev BM, Mihai-Zamfir E, Caraveţeanu DC, Al Krayem N, Brăila M, Velea R, Neacşu A Abstract The cervical cancer is the worldwide second neoplasia in women, after the breast cancer. The incidence of invasive carcinoma in pregnancy is 1÷2000 to 1÷10 000 pregnancies. In most of the studies, almost all the patients had microinvasive carcinoma or limited cervical carcinoma at the cervix level. In the uteroplacental apoplexy, pathologically, retroplacental hematoma is formed while the fetus is still in the uterus. When speaking about the uteroplacental apoplexy, the fetal mortality...
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Abstract The "ovarian cycle" is an exquisite and dynamic endocrine system that includes ovarian events, hypothalamic-pituitary interactions, uterine endometrial and myometrial changes during implantation and pregnancy, cervical alterations in structure, and breast development. The ovarian cycle and the steroid hormones produced by the ovary also impact epithelial cancer development in the ovary, uterus, cervix, and breast. This chapter provides a personal view of recent developments that occur in this complex endocrine environment. PMID: 29544627 [PubMed - in process]
Source: Vitamins and Hormones - Category: Endocrinology Authors: Tags: Vitam Horm Source Type: research
More News: Babies | Biology | Cancer | Cancer & Oncology | Cancer of the Uterus | Children | Health | Medical Ethics | Middle East Health | OBGYN | Ovarian Cancer | Ovaries | Parenting | Pregnancy | Reproduction Medicine | Royal College of Obstetricians and Gynaecologists | Science | Study | Sweden Health | Transplants | Women