Progress toward creating broad-spectrum antiviral

(University of Washington Health Sciences/UW Medicine) UW researchers working in collaboration with Kineta Inc. and the University of Texas at Galveston have shown that making a drug-like molecule to turn on innate immunity can induce genes to control infection in several -known viruses. The findings published in the Journal of Virology show promising evidence for creating a broad spectrum antiviral that can suppress a range of RNA viruses, including West Nile, dengue virus, hepatitis C, influenza A, respiratory syncytial, Nipah, Lassa and Ebola.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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ConclusionThese results suggested that IFN-γ plays an important role in acute lung injury induced by severe influenza A(H1N1)pdm09 infection, and monoclonal antibodies against IFN-γ could be useful as a potential therapeutic remedy for future influenza pandemics.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
Current challenges: from the path of "original antigenic sin" towards the development of universal flu vaccines. Int Rev Immunol. 2019 Nov 09;:1-16 Authors: Biswas A, Chakrabarti AK, Dutta S Abstract Annual flu led by influenza viruses is contemplated to be one of the foremost global health challenges due to its rapid spread leading to the life-threatening epidemic or pandemic. An enormous number of people die due to flu and its associated intricacies every year. Annual vaccination is considered to be the gold standard strategy to protect the individual from acquiring infection and further de...
Source: International Reviews of Immunology - Category: Allergy & Immunology Tags: Int Rev Immunol Source Type: research
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Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
A recap of Tuesday’s top stories: Pneumonia number one killer of children; Australia’s wildfires rage on; Ebola vaccine gets green light; new child labour and trafficking study; Malnutrition soars in Latin America and Caribbean; Intellectual Property chief encourages innovation.
Source: UN News Centre - Health, Poverty, Food Security - Category: International Medicine & Public Health Source Type: news
A new CRISPR technology used to target a gene might be an effective way to eradicate chronic hepatitis B infection, investigators report.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Gastroenterology News Source Type: news
U.S. drugmaker Merck &Co Inc on Monday received approval from the European Commission to market its Ebola vaccine.
Source: CBC | Health - Category: Consumer Health News Tags: News/Health Source Type: news
In this report, a 60 years old woman with a past medical history of significant chronic kidney disease undergoing regular hemodialysis, chronic constipation and hepatitis B was admitted to our neurology clinic because of acute intracerebral hemorrhage. She had confusion and right hemiplegia in her neurological examination and required urinary catheterization due to immobilization. Red coloration was observed in urine on the tenth hospital day. Although this coloration was thought to be hematuria, according to urine examination it was not hematuria. Then urine color turned into purple within two days. The next day, because ...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
Based on discussions with various folk at scientific and industry conferences earlier this year, regarding whether or not our rejuvenation research, development, and advocacy community is challenging to approach and understand as an outsider, I recently put together an introductory document for entrepreneurs entitled How to Start a Biotech Company in the Longevity Industry (PDF). Given my experiences, it is primarily aimed at entrepreneurs with previous experience in other industries, who are now interested in helping to treat aging as a medical condition and there by greatly improve the human condition. The young...
Source: Fight Aging! - Category: Research Authors: Tags: Activism, Advocacy and Education Source Type: blogs
Authors: Ruszel N, Kubisa B, Lisowski P, Piotrowska M, Kubisa MJ, Brykczyński M, Wojtyś M, Pieróg J, Czarnecka M, Wójcik J, Wójcik N, Sielicki P, Bielewicz M, Grodzki T PMID: 31708987 [PubMed]
Source: Polish Journal of Cardio-Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Kardiochir Torakochirurgia Pol Source Type: research
Kinyoun Lecture Ian A. Wilson, D. Phil., D.Sc., Hansen professor of structural biology and chair, department of integrative structural and computational biology at The Scripps Research Institute, La Jolla, Calif., will deliver the 2019 Joseph J. Kinyoun Memorial Lecture on Tuesday, November 19, at 3 p.m. in Lipsett Amphitheater, Bldg. 10. His presentation is titled, “ Structure-assisted Design of Universal Vaccines and Therapeutics against Influenza Virus. ” Wilson will explain how insights gained through structural biology approaches are aiding in devising new ways to treat or prevent influenza. The health and...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
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