Holiday tips for those caring for family members affected by Alzheimer's disease and other dementias

As part of the Dementia-Capable Wisconsin Initiative , the Wisconsin Department of Health Services (DHS), in partnership with the Alzheimer’s Association , and your local Aging and Disability Resource Center (ADRC), would like to share some advice about ways to adapt holiday celebrations to meet the needs of a family member with dementia, and still maintain the joy of the season. “...(see release)
Source: Wisconsin DHFS Press Releases - Category: Hospital Management Authors: Source Type: news

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In this study we describe a heterogeneous network-based data set for Alzheimer's disease (HENA). Additionally, we demonstrate the application of state-of-the-art graph convolutional networks, i.e. deep learning methods for the analysis of such large heterogeneous biological data sets. We expect HENA to allow scientists to explore and analyze their own results in the broader context of Alzheimer's disease research. PMID: 31413325 [PubMed - in process]
Source: Genomics Proteomics ... - Category: Genetics & Stem Cells Authors: Tags: Sci Data Source Type: research
DISCUSSION: The German version of the CAMDEX-DS provides an internationally recognized tool for the diagnostics and monitoring of cognitive decline in Down's syndrome. Furthermore, the German version can standardize medical care of these patients. In particular it provides a means of participation in international research trials for this at risk population. PMID: 31399752 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Gerontologie und Geriatrie - Category: Geriatrics Authors: Tags: Z Gerontol Geriatr Source Type: research
DiscussionExperiences of housing loss continued to be significantly associated with cognitive disability even six years after the disaster.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
In this study we show, for the first time, significant alterations in cholesterol efflux capacity in adolescents throughout the range of BMI, a relationship between six circulating adipocyte-derived EVs microRNAs targeting ABCA1 and cholesterol efflux capacity, and in vitro alterations of cholesterol efflux in macrophages exposed to visceral adipose tissue adipocyte-derived EVs acquired from human subjects. These results suggest that adipocyte-derived EVs, and their microRNA content, may play a critical role in the early pathological development of ASCVD. Commentary on the Developing UK Government Position on Hea...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This article summarizes the evidence for translation into action. PMID: 31327392 [PubMed - in process]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
This article summarizes the evidence for translation into action.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
In this study, we identify a link between members of the genus Veillonella and exercise performance. We observed an increase in Veillonella relative abundance in marathon runners postmarathon and isolated a strain of Veillonella atypica from stool samples. Inoculation of this strain into mice significantly increased exhaustive treadmill run time. Veillonella utilize lactate as their sole carbon source, which prompted us to perform a shotgun metagenomic analysis in a cohort of elite athletes, finding that every gene in a major pathway metabolizing lactate to propionate is at higher relative abundance postexercise. Us...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions: Our analysis extends recent work by revealing specific benefits for instrumental activities of daily living for individuals in the early stages of AD and supports the value of exercise for individuals with cognitive impairment.
Source: Journal of Geriatric Physical Therapy - Category: Physiotherapy Tags: Research Reports Source Type: research
Authors: Uekusa S Abstract Using qualitative interviews, this research explores the experiences of residential nursing home caregivers in Fukushima, who provided support to elderly sufferers of Alzheimer's or other related forms of dementia during the 2011 Great East Japan Earthquake and Tsunami. Although the disaster vulnerability of care recipients such as the elderly, infirmed, disabled, and sufferers of dementia have been studied, their caregivers' disaster experiences, vulnerability and resilience have remained comparatively invisible and under-investigated. Their experiences suggest that coping with the disas...
Source: Social Work in Public Health - Category: International Medicine & Public Health Tags: Soc Work Public Health Source Type: research
AbstractAlzheimer ’s disease (AD) is the most prevalent neurodegenerative disease that results in progressive dementia, and exhibits high disability and fatality rates. Recent evidence has demonstrated that neuroinflammation is critical in the pathophysiological processes of AD, which is characterized by the activa tion of microglia and astrocytes. Under different stimuli, microglia are usually activated into two polarized states, termed the classical ‘M1’ phenotype and the alternative ‘M2’ phenotype. M1 microglia are considered to promote inflammatory injury in AD; in contrast, M2 microglia e...
Source: Inflammopharmacology - Category: Drugs & Pharmacology Source Type: research
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