Association between omentin-1, bone metabolism markers, and cytokines of the RANKL/RANK/OPG system in girls with anorexia nervosa.

CONCLUSIONS: The relationship between omentin-1, bone markers, and the OC/CTx and OPG/sRANKL ratios observed in girls with AN indicates the involvement of this adipokine in the regulation of dynamic balance between bone formation and resorption processes. Omentin-1 might exert a negative effect on bone remodelling in girls with AN by inhibiting both bone formation and resorption. The OPG/sRANKL system plays an important role in the latter. (Endokrynol Pol 2015; 66 (6): 514-520).
PMID: 26662650 [PubMed - in process]

Source: Endokrynologia Polska - December 18, 2015 Category: Endocrinology Authors: Gołąbek K, Ostrowska Z, Ziora K, Oświęcimska J, Świętochowska E, Marek B, Kajdaniuk D, Strzelczyk J, Kos-Kudła B Tags: Endokrynol Pol Source Type: research