Role of dopaminergic neurotransmission in pathophysiology of action tremor in Parkinson's disease.

CONCLUSION: Our study confirms the good correlation between putamen DAT binding and bradykinesia and the lack of correlation between putamen DAT binding and rigidity/RT. In addition, we failed to found any significant correlation between putamen DAT binding and severity of action tremor, which suggests a contribution of non-dopaminergic mechanisms to its pathophysiology. PMID: 26665206 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26665206?dopt=Abstract

Source: Hellenic Journal of Nuclear Medicine - December 17, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research