ADHD Patients Show Weaker Connections in Brain Networks Tied to Focus

But more research is needed before scans could be used to diagnose disorder, experts say Source: HealthDay Related MedlinePlus Page: Attention Deficit Hyperactivity Disorder
Source: MedlinePlus Health News - Category: Consumer Health News Source Type: news

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Abstract The study aimed to investigate the pathologic mechanism of functional brain regions in attention-deficit hyperactivity disorder (ADHD) patients through making comparisons of normal and ADHD children from the perspective of the network nodes of brain network and the intensity of functional connection between bilateral of hemispheres by resting-state functional magnetic resonance imaging (fMRI). Thirty-five ADHD and forty-two children were examined by resting-state functional magnetic resonance imaging (fMRI) scans. Data analysis was done via the degree centrality (DC) and voxel-mirrored homotopic connectiv...
Source: International Journal of Developmental Neuroscience - Category: Neuroscience Authors: Tags: Int J Dev Neurosci Source Type: research
This study aimed to explore whether differential GM volume is associated with differential miRNA levels in ADHD patients. We recruited a total of 30 drug-naïve patients with ADHD (mean age 10.6 years) and 25 healthy controls (mean age 10.6 years) that underwent a single session of 3.0-T whole brain structural MRI scanning. RNA samples from the participants' white blood cells were collected to identify the ΔCt values of three miRNAs (miR-30e-5p, miR-126-5p, and miR-140-3p) using the real-time quantitative reverse transcription polymerase chain reaction. In comparison to the control group, ADHD patients ...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
Purpose of review To give an update on recent imaging studies probing positron emission tomography (PET) as a tool for improving biomarker-guided diagnosis of neuropsychiatric disorders. Recent findings Several studies confirmed the value of imaging of regional neuronal activity and imaging of dopaminergic, serotonergic, and other neuroreceptor function in the diagnostic process of neuropsychiatric disorders, particularly schizophrenia, depression/bipolar disorder, substance use disorders, obsessive compulsive disorders (OCD), and attention-deficit/hyperactivity disorder. Additionally, imaging brain microglial activat...
Source: Current Opinion in Neurology - Category: Neurology Tags: NEUROIMAGING: Edited by Stefan Klöppel Source Type: research
This study aimed to explore whether differential GM volume is associated with differential miRNA levels in ADHD patients. We recruited a total of 30 drug-na ïve patients with ADHD (mean age 10.6 years) and 25 healthy controls (mean age 10.6 years) that underwent a single session of 3.0-T whole brain structural MRI scanning. RNA samples from the participants’ white blood cells were collected to identify the ΔCt values of three miRNAs (miR-30e-5p, m iR-126-5p, and miR-140-3p) using the real-time quantitative reverse transcription polymerase chain reaction. In comparison to the control group, ADHD p...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Neuroscience Source Type: research
The objective of this population-based study was to examine the association between synthetic oxytocin use during labor and hyperactivity/inattention problems in the children.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
Aortic mycotic pseudoaneurysm in pediatric population is rare and carries a high mortality (1). The institutional research board approved publication of this case report. A 10-year-old male with attention deficit hyperactivity disorder and developmental delay presented with massive upper gastrointestinal (GI) bleeding and hypovolemic shock. His family reported a 12-day history of stridor and abdominal pain. Chest computed tomography (CT) scan showed a 6  × 5 × 4 cm pseudoaneurysm arising from the posterior wall of aortic arch between the left common carotid and subclavian arteries with mass effect on ...
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
Conclusions: Our results indicate the tendency to deviate from a more centralized organization (star-like topology) towards a more decentralized organization (line-like topology) in the frontal-parietal attention network of children with ADHD. This represents a more random network that is associated with impaired global efficiency and network decentralization. These changes appear to reflect clinically relevant phenomena, and hold promise as markers of disease progression.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
CONCLUSION: Prior to treatment, coeliac disease patients reported significantly more symptoms than healthy controls on ASRS and HADS. The differences disappeared after a minimum of 12 months on a gluten-free diet. PMID: 31050907 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Rui Yan1, ShiWan Tao1, HaiYan Liu1, Yu Chen1, JiaBo Shi1, YuYin Yang1, RongXin Zhu1, ZhiJian Yao1,2* and Qing Lu3,4*1Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China2Nanjing Brain Hospital, Medical School of Nanjing University, Nanjing, China3School of Biological Sciences and Medical Engineering, Southeast University, Nanjing, China4Child Development and Learning Science, Key Laboratory of Ministry of Education, Nanjing, ChinaBackground: Major depressive disorders often involve somatic symptoms and have been found to have fundamental differences from non-somatic depressi...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion: Although emotion dysregulation is regarded as a core symptom of ADHD, explicit reappraisal does not seem to be impaired in adult patients. However, increased activation of the ACC implies stronger implicit emotion regulation induced by negative stimuli. This might be explained by emotional hyperresponsivity in patients with ADHD compared with controls. PMID: 31025560 [PubMed - as supplied by publisher]
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research
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