Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS Study)

Background:
To validate a new practical Sepsis Severity Score for patients with complicated intra-abdominal infections (cIAIs) including the clinical conditions at the admission (severe sepsis/septic shock), the origin of the cIAIs, the delay in source control, the setting of acquisition and any risk factors such as age and immunosuppression.
Methods:
The WISS study (WSES cIAIs Score Study) is a multicenter observational study underwent in 132 medical institutions worldwide during a four-month study period (October 2014-February 2015). Four thousand five hundred thirty-three patients with a mean age of 51.2 years (range 18–99) were enrolled in the WISS study.
Results:
Univariate analysis has shown that all factors that were previously included in the WSES Sepsis Severity Score were highly statistically significant between those who died and those who survived (p 

Source: World Journal of Emergency Surgery - December 16, 2015 Category: Emergency Medicine Authors: Massimo SartelliFikri Abu-ZidanFausto CatenaEwen GriffithsSalomone Di SaverioRaul CoimbraCarlos OrdoñezAri LeppaniemiGustavo FragaFederico CoccoliniFerdinando AgrestaAsrhaf AbbasSaleh Abdel KaderJohn AgboolaAdamu AmhedAdesina AjibadeSeckin AkkucukBandar Source Type: research