Benign familial pemphigus ( Hailey-Hailey disease). White, Forrest; Shvartsbeyn, Marianna; Meehan, Shane A; Urbanek, Richard W

A 56-year-old man presented with a 15-year history of scaly red plaques on the trunk and axillae. Skin biopsy was consistent with Hailey-Hailey disease. His condition was refractory to multiple therapies, which included topical and oral antibiotics and topical, intralesional, and oral glucocorticoids. Treatment with subcutaneous botulinum toxin type A at the axillae and on the back led to a nearly complete resolution of plaques in those areas. Botulinum toxin type A should be considered in patients with extensive Hailey-Hailey disease who are fail traditional therapies.
Source: Dermatology Online Journal - Category: Dermatology Source Type: research