Promising cancer therapy advanced by chemical explanation

Radiation therapy: A chilling word that creates images of burn-injuries where the cancer killing ray went through the skin. For decades research hospitals have been investigating the alternative method Hadron therapy, or particle therapy, where runaway cells are bombarded with 'naked' atomic nuclei or protons. When the particles pass through sick cells the collision creates chemical reactions preventing further cell division. Now researchers have discovered an unknown reaction caused by the therapy.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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HOUSTON (AP) — Kristin Crump and her two kids put damp cloths over their mouths on Thursday for the short walk from their suburban Houston front door to their car, defying an order to remain inside because of dangerous fumes coming from burned-out petrochemical tanks a couple of miles away. For the second time in three days, they were heading to a relative's house, worried about what they've been breathing since a massive fire broke out Sunday at the Intercontinental Terminals Company in Deer Park and not believing officials' assurances that they were safe. "I do not fully trust what they say," said Crump, ...
Source: JEMS: Journal of Emergency Medical Services News - Category: Emergency Medicine Tags: News Source Type: news
Abstract In the 2015 Ken Burns documentary, Cancer: The Emperor of All Maladies, based on Siddhartha Mukherjee's The Emperor of All Maladies, the 2011 nonfiction award-winning biography about cancer, we are introduced to the first pediatric patient who received an experimental cellular therapy at Children's Hospital of Philadelphia. The outcomes for that patient, initially treated in 2012 and now almost seven years into survivorship, led to the development of clinical trials with commercially developed chimeric antigen receptor (CAR) T-cell products. PMID: 30880818 [PubMed - in process]
Source: Clinical Journal of Oncology Nursing - Category: Nursing Authors: Tags: Clin J Oncol Nurs Source Type: research
Association of prostate cancer SLCO gene expression with Gleason grade and alterations following androgen deprivation therapy, Published online: 19 March 2019; doi:10.1038/s41391-019-0141-6Association of prostate cancer SLCO gene expression with Gleason grade and alterations following androgen deprivation therapy
Source: Prostate Cancer and Prostatic Diseases - Category: Urology & Nephrology Authors: Source Type: research
Authors: Tempero MA, Malafa MP, Chiorean EG, Czito B, Scaife C, Narang AK, Fountzilas C, Wolpin BM, Al-Hawary M, Asbun H, Behrman SW, Benson AB, Binder E, Cardin DB, Cha C, Chung V, Dillhoff M, Dotan E, Ferrone CR, Fisher G, Hardacre J, Hawkins WG, Ko AH, LoConte N, Lowy AM, Moravek C, Nakakura EK, O'Reilly EM, Obando J, Reddy S, Thayer S, Wolff RA, Burns JL, Zuccarino-Catania G Abstract The NCCN Guidelines for Pancreatic Adenocarcinoma discuss the diagnosis and management of adenocarcinomas of the exocrine pancreas and are intended to assist with clinical decision-making. These NCCN Guidelines Insights discuss imp...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - Category: Cancer & Oncology Tags: J Natl Compr Canc Netw Source Type: research
 We all have habits we’d rather not have, whether it’s smoking, emotional eating, or any of a hundred other things. And it’s likely that we’ve all, at one point or another, tried to break one or more of them, only to have the break be only temporary. What’s the secret to permanent habit change? Listen to this episode and find out! Subscribe to Our Show! And Remember to Review Us! About Our Guest Judson Brewer, MD, PhD is a thought leader in the field of habit change and the “science of self-mastery,” having combined over 20 years of experience with mindfu...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Habits Mindfulness The Psych Central Show breaking habits Gabe Howard Vincent M. Wales Source Type: blogs
Conclusions: The CRC stage and interval since last colonoscopy were not correlated, which is in conflict with the accelerated adenoma-carcinoma paradigm. We have previously reported that more frequent colonoscopy is not associated with lower incidence of CRC in path_MMR carriers as was expected. In contrast, point estimates showed a higher incidence with shorter intervals between examinations, a situation that may parallel to over-diagnosis in breast cancer screening. Our findings raise the possibility that some CRCs in path_MMR carriers may spontaneously disappear: the host immune response may not only remove CRC precurso...
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: Hered Cancer Clin Pract Source Type: research
avath P, Tung N, Pohlmann PR, Burns R, Rimawi MF, Krop IE, Wolff AC, Winer EP, Lin NU, Translational Breast Cancer Research Consortium Abstract PURPOSE: Evidence-based treatments for metastatic, human epidermal growth factor receptor 2 (HER2)-positive breast cancer to the CNS are limited. We previously reported modest activity of neratinib monotherapy for HER2-positive breast cancer brain metastases. Here we report the results from additional study cohorts. PATIENTS AND METHODS: Patients with measurable, progressive, HER2-positive brain metastases (92% after receiving CNS surgery and/or radiotherapy) received...
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: J Clin Oncol Source Type: research
Exactly eight years ago, an earthquake off the east coast of Japan set a massive tsunami on a collision course with the Fukushima Daiichi nuclear power plant. The wall of water overwhelmed the reactors’ cooling mechanisms and over the next four days the plant suffered three nuclear meltdowns. It became the world’s worst nuclear disaster since Chernobyl. In response, Germany, Switzerland and some others around the world accelerated their plans to ditch nuclear power as an energy source. Nuclear power is virtually free of emissions. By contrast, we burn coal and gas at industrial scale to make electricity, pumpin...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized Environment Source Type: news
Publication date: Available online 8 March 2019Source: Prostaglandins &Other Lipid MediatorsAuthor(s): Ahmed E.M. Elhassanny, Daniel A. Ladin, Eman Soliman, Hussam Albassam, Andrew Morris, Robert Kobet, Kathleen Thayne, Colin Burns, Allison S. Danell, Rukiyah Van DrossAbstractThe combined incidence of melanoma and non-melanoma skin cancer (NMSC) is greater than the incidence of all other malignancies in the US. Previously, we demonstrated that the endocannabinoid, arachidonoyl-ethanolamide (AEA), was a potent inducer of apoptosis in NMSC. The metabolism of AEA to the prostaglandin, PGD2-EA, was a prerequisite for AEA c...
Source: Prostaglandins and Other Lipid Mediators - Category: Lipidology Source Type: research
CONCLUSIONS: A precise understanding of the burden of disease profile is essential for national, provincial and district budgeting and resource allocation. Ongoing surveillance such as that performed in the study provides this critical information. PMID: 30834864 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
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