Strategies for developing new antiviral flu drugs

New analysis of the influenza A virus by scientists at the University of Hertfordshire shows potential for developing new anti-viral drugs which are more likely to be universally effective against the flu virus originating from avian, swine or human virus strains.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

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China reported a new H5N6 bird flu outbreak in the southwestern province of Yunnan, the agriculture ministry said on Friday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Hero ínas de la vida real: Adamari López aprendió a escuchar a su cuerpo ... Está en camino a la recuperación después de una peligrosa influenza que casi le roba la vida. ... por: Jennifer García Ca...
Source: AARP.org News - Category: American Health Source Type: news
This study aims to describe the spatial and temporal characteristics of human infections with H7N9 virus in China using data from 19 February 2013 to 30 September 2017 extracted from Centre for Health Protection of the Department of Health (CHP) and electronic databases managed by China’s Center for Disease Control (CDC) and provincial CDCs synthetically using the Geographic Information System (GIS) software ArcMap™ 10.2 and SaTScan. Based on the multiple analyses of the A(H7N9) epidemics, there was a strong seasonal pattern in A(H7N9) virus infection, with high activity in the first quarter of the year...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
AbstractThe synaptonemal complex is an evolutionarily conserved, supramolecular structure that holds the homologous chromosomes together during the pachytene stage of the first meiotic prophase. Among vertebrates, synaptonemal complex dynamics has been analyzed in mouse spermatocytes following the assembly of its components from leptotene to pachytene stages. With few exceptions, a detailed study of the disassembly of SCs and the behavior of SC components at recombination sites at the onset of diplotene has not been accomplished. Here, we describe for the first time the progressive disassembly of the SC in chicken oocytes ...
Source: Chromosoma - Category: Genetics & Stem Cells Source Type: research
(Reuters Health) - When influenza-like illnesses spread in the community, death rates go up for patients on dialysis, a new study shows.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Condition:   Influenza Interventions:   Biological: Grippol® Quadri;   Biological: Grippol® Plus, trivalent (Yamagata lineage);   Biological: Grippol® Plus, trivalent (Victoria lineage) Sponsor:   NPO Petrovax Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We refer transmission of infections in India which have implications for Pakistan [1]. As compared to Pakistan, the range and burden of infectious diseases are enormous in India including Severe Acute Respiratory Syndrome (SARS) contagion in 2002 –2003, Influenza A virus epidemic of 2006 (avian influenza), 2007 Equine influenza, Swine flu pandemic outbreaks in 2009 and 2014 [2]. Moreover, episodes of infectious diseases continue to rise in India, with a recent surge of chikungunya and dengue cases in 2016 [1].
Source: Travel Medicine and Infectious Disease - Category: Infectious Diseases Authors: Source Type: research
The Zika virus attracted many headlines this winter, but a recent admission by the chief medical officer at a leading vaccine manufacturer -- that the world is ill-prepared to deal with pandemic outbreaks -- underscores a fundamental problem. To ensure safety and efficacy, the federal government's regulatory approval process for new vaccines may extend development timelines for years. So when The New York Times reports that "eighteen organizations are working on developing a vaccine for the Zika virus," it is likely that those companies will labor for a very long time. Vaccinations rightly require stri...
Source: Science - The Huffington Post - Category: Science Source Type: news
Abstract: History provides us several illustrations where epidemic outbreaks have led to biological disasters. Accidental or deliberate release of harmful micro-organisms can also lead to biological disasters. With the advent of bio-terrorism, there is a growing realisation that biological agents can also be used as weapons of mass destruction. The spread of Spanish Influenza of 1917-18, the Human Immunodeficiency Virus (HIV) / Acquired Immuno Deficiency Syndrome (AIDS), Severe Acute Respiratory Syndrome (SARS), Swine Flu (H1N1), Avian Influenza (H5N1), Middle East Respiratory Syndrome (MERS), dengue, chikunguniya, Ebola o...
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Type: Invited Presentation Source Type: research
Conclusions: By referring to the previous studies, we suggest that proteins including FAN, CPSF2, AGO1, AGO2, PAX5, STAT1 and PDGFB can be used as therapeutic targets of IAV infection.J Mol Microbiol Biotechnol 2015;25:311-319
Source: Journal of Molecular Microbiology and Biotechnology - Category: Microbiology Source Type: research
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