Schizophrenic psychoses with affect-dominant symptoms : Contribution to a system-specific approach.

DISCUSSION: The concept of an affect-dominant subtype of schizophrenia was not entirely convincing with respect of the heterogeneous course of the patients described. Nevertheless, the system-specific approach may hold promise for the future regarding further neurobiological research. PMID: 26646613 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - Category: Neurology Authors: Tags: Nervenarzt Source Type: research

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ConclusionesLos resultados indican que los síntomas negativos y el funcionamiento premórbido predicen directamente la funcionalidad, mientras que los factores cognitivos muestran interacciones más complejas con los síntomas negativos y la funcionalidad. Estos resultados deberían ser considerados para nuevas estrategias de intervención.AbstractIntroductionAlthough it is well-known that several factors such as symptoms and cognition are related with functional outcome in schizophrenia, the complex nature of the disorder makes necessary to study their interaction by means of a more an...
Source: Revista de Psiquiatria y Salud Mental - Category: Psychiatry Source Type: research
ConclusionsThese findings provided only modest support for the temporal dynamics of positive emotion conceptualization because they revealed no evidence for: 1) specific anticipatory pleasure deficits in schizophrenia-spectrum participants compared to controls; 2) significant reductions in anticipatory pleasure relative to consummatory pleasure in schizophrenia-spectrum participants.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: December 2019Source: Neuroscience &Biobehavioral Reviews, Volume 107Author(s): Sean P. Carruthers, Tamsyn E. Van Rheenen, Caroline Gurvich, Philip J. Sumner, Susan L. RossellAbstractThe aim of the present review was to systematically summarise our current understanding of the structure of the cognitive heterogeneity that exists within schizophrenia spectrum disorder (SSD). Fifty-two relevant studies were identified from January 1980 to March 2019 that investigated cognitive subgroups within SSD. Twenty-five studies employed classification criteria based on current neuropsychological function, 14 stu...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
We report here the derivation of familial iPSC lines from two controls and three ASD patients carrying NRXN1α+/−, using a non-integrating Sendai viral kit. The genotype and karyotype of the resulting iPSCs were validated by whole genome SNP array. All iPSC lines expressed comparable levels of pluripotency markers and could be differentiated into three germ layers.
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Authors: Santarelli V, Marucci C, Collazzoni A, Rossetti MC, Pizziconi G, Pacitti F, Stratta P, Rossi A, Rossi R Abstract The relationship between subjective appraisal of cognitive deficits and symptom severity in schizophrenia is unclear. Insight reportedly affects both factors. Our aim is to further asses the relationship between subjective perception of cognitive deficits, symptom severity and lack of insight as a mediator variable. 109 subjects with schizophrenia were evaluated. Positive and Negative Syndrome Scale (PANSS) was modelled as independent variable, Subjective Scale to Investigate Cognition in Schizo...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
This study examined mental health perceptions held by Chinese immigrant parents of youth. METHODS: Eighteen parents (13 female, 5 male), who identified as having children between the ages of 13 and 21 years, participated in audio-recorded interviews using five vignettes depicting depression with and without a somatic emphasis, schizophrenia with paranoid features, attenuated psychosis syndrome, and social anxiety in youth. Questions about potential causes, likely diagnosis, and health-seeking behaviors in relation to these vignettes were asked. Interviews were analyzed for themes using a deductive-inductive hybrid appr...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
Authors: Li W, Yang Y, Hong L, An FR, Ungvari GS, Ng CH, Xiang YT Abstract OBJECTIVE: Aggression is common in patients with schizophrenia and is clinically significant, but its prevalence is inconsistent across studies. This is a meta-analysis of the prevalence of aggression and its associated factors in patients with schizophrenia. METHODS: PubMed, EMBASE, PsycINFO, the Cochrane Library, Medline and Web of Science databases were systematically searched. Studies that reported the prevalence of aggression in patients with schizophrenia using the Modified Overt Aggression Scale (MOAS) were included and analyzed u...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
CONCLUSIONS: Forty-one percent of the respondents did not feel comfortable with clozapine prescription. Major concerns cited included the side effect profile as well as lack of experience and training. The majority of the respondents felt that they would be more comfortable prescribing clozapine if they had the opportunity to train in a clozapine clinic. PMID: 31713078 [PubMed - as supplied by publisher]
Source: The Journal of American Association of Directors of Psychiatric Residency Training - Category: Psychiatry Tags: Acad Psychiatry Source Type: research
DISCUSSION: ED utilization after outpatient hand surgery is low, with postoperative pain being the most common cause of an ED visit at all time points. Nearly 98% of patients presenting to the ED for postoperative pain are subsequently discharged home. LEVEL OF EVIDENCE: Level III, Retrospective Cohort. PMID: 31714419 [PubMed - as supplied by publisher]
Source: The Journal of the American Academy of Orthopaedic Surgeons - Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research
Incorporating genetic data into a clinical tool that predicts whether a person will develop schizophrenia can improve the accuracy of this tool, according to astudy appearing inAJP in Advance.Diana Perkins, M.D., M.P.H., of the University of North Carolina and colleagues assessed whether polygenic risk scores (PRS) could be used as part of a clinical assessment of schizophrenia risk. A PRS reflects how many individual genetic variants associated with schizophrenia a person has; the higher an individual ’s PRS, the greater his or her genetic risk of developing schizophrenia. They looked at health data from 764 young a...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance Diana Perkins DNA genetic data North American Prodrome Longitudinal Study polygenic risk score psychosis schizophrenia Source Type: research
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