Vigor of peristalsis during multiple rapid swallows is inversely correlated with acid exposure time in patients with NERD
Abstract BackgroundMultiple rapid swallowing (MRS) during high‐resolution manometry (HRM) is increasingly utilized as provocative test to assess esophageal peristaltic reserve. The aim of this study was to evaluate the correlation between MRS response and impedance and pH (MII‐pH) parameters in endoscopy negative heartburn (ENH) patients. MethodsWe enrolled consecutive ENH patients, who underwent HRM and MII‐pH study, with a selected MII‐pH profile: abnormal MII‐pH (pH+/MII+); normal MII‐pH (pH−/MII−). HRM was performed with 10 wet swallows (WS) and one MRS. Mean distal contractile integral (DCI) during WS and MRS were calculated. MII‐pH parameters including acid exposure time (AET), reflux events, baseline impedance levels (BI) and the efficacy of chemical clearance evaluated with the postreflux swallow‐induced peristaltic wave (PSPW) index were measured. Key ResultsWe analyzed 103 patients: 49 MII+/pH+ (27 male), and 54 MII−/pH− (19 male). Mean age was similar between the two groups. As expected, mean AET and number of refluxes were higher in pH+/MII+ (p
In conclusion, mobile phones presented the presence of clinically relevant microorganisms. PMID: 31967261 [PubMed - in process]
ConclusionThe surgical option remains the standard of treatment and can be performed safely in Gastro-Gastric Fistula Type II. Orogastric tube accidental complications should be identified preferably perioperatively and measures of prevention should be implied to avoid such events.
ConclusionVE is a new useful tool for the preoperative collection of data on small polypoid lesions in the small bowel.
Scientists at Northwestern University in Illinois studied 166 indoor dust samples and found that bacteria living within them were able to share antibiotic resistant genes with each other.
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Conclusion: Although AIG is rare in children, pediatric gastroenterologists and pathologists should have a heightened suspicion for this entity in those patients with a history of autoimmune disorders and/or pernicious anemia.
Conclusions: Overall, gastrostomy placement was not associated with an increase in acid exposure on 24-hour multichannel intraluminal impedance pH monitoring. Similarly, the prevalence of gastro-oesophageal reflux-related symptoms did not change after gastrostomy.
ConclusionAccording to the notable anti-inflammatory effect in vitro and its joint protective effects on a septic mouse model, SESLA might act as an adjuvant drug candidate for sepsis, even those caused by antibiotic-resistant bacteria, e.g., CRKP.Graphical abstract
Condition: Gastroesophageal Reflux Intervention: Procedure: Laparoscopic sleeve gastrectomy Sponsor: Chinese University of Hong Kong Not yet recruiting