Additive antitumour response to the rabbit VX2 hepatoma by combined radio frequency ablation and toll like receptor 9 stimulation

Conclusions
The combination of TLR9 stimulation with RFA resulted in a potentiated antitumour T cell response and cytotoxicity in the VX2 tumour model. Only this combination prevented subsequent tumour spread and resulted in a significantly improved survival, justifying the need for further exploration of the combination of ablative therapies and TLR9 agonists in liver cancer.

Source: Gut - December 8, 2015 Category: Gastroenterology Authors: Behm, B., Di Fazio, P., Michl, P., Neureiter, D., Kemmerling, R., Hahn, E. G., Strobel, D., Gress, T., Schuppan, D., Wissniowski, T. T. Tags: Hepatic cancer Hepatology Source Type: research