Autism Spectrum Disorder Linked To PCOS In Eye-Opening New Study

Women who suffer from polycystic ovary syndrome, or PCOS, are 59 percent more likely to give birth to a child with autism spectrum disorder than women without the disorder, according to a study published in the journal Molecular Biology in December.  PCOS is a hormonal disorder that affects as many as 1 in 10 women and is the leading cause of infertility. The disorder, caused by cysts in the ovaries, is marked by abnormally high levels of the male hormone androgen, which can lead to acne, excessive hair growth, weight gain and ovulation problems. While all women produce androgens, women with PCOS overproduce them and this may account for the difference, according to the study's lead researcher. "Women with PCOS have increased levels of androgens in their bodies compared to women without PCOS, even during pregnancy,"  Kyriaki Kosidou, a psychiatrist and researcher at Karolinska Institutet in Stockholm and lead author of the study, told The Huffington Post. Those androgens could subtly influence the fetus's developing brain and nervous system, Kosidou said. The risk was even higher among women with PCOS who were also obese, perhaps because overweight women with PCOS tend to have even higher androgen levels than average-weight women with the disorder. Although ASD is five times more common in boys than in girls, according to the National Institutes of Health, babies born to mothers with PCOS in the study had the same risk, regardless of th...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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This study aimed to evaluate the therapeutic effect of folic acid (FA) on diabetic retinopathy (DR) in a genetic mouse model of obese type 2 diabetes mellitus (T2D). C57BL/KsJ-db/db(db/db) T2D mice were divided into control, FA, metformin (MET), and FA plus MET groups (n = 10/group). Serum levels of glucose, glycated hemoglobin, and insulin were determined weekly. The retinal thickness was measured using optical coherence tomography (OCT) at 4 weeks after treatments. The retinal expression and serum levels of vascular formation, inflammation, and oxidative stress-associated molecules were examined. Our results demonstrated...
Source: Ophthalmic Research - Category: Opthalmology Source Type: research
Publication date: June 2019Source: Journal of Functional Foods, Volume 57Author(s): Han-Jun Kim, Eun-Ji Choi, Hyo Sung Kim, Chan-Woong Choi, Sik-Won Choi, Sun-Lim Kim, Woo-Duck Seo, Sun Hee DoAbstractPostmenopausal obesity is becoming a serious global health concern. Soyasaponin Ab (SA) inhibits adipocyte differentiation; however, the preventive and therapeutic potential of SA in postmenopausal obesity has not been clearly established. Here, we investigated the anti-obesity effects of SA in postmenopausal obesity in vitro and in vivo. SA inhibited adipocytic differentiation of 3T3-L1 cells and reduced lipid accumulati...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Background: The circadian timing system or circadian clock plays a crucial role in many biological processes, such as the sleep-wake cycle, hormone secretion, cardiovascular health, glucose homeostasis, and body temperature regulation. Energy balance is also one of the most important cornerstones of metabolic processes, whereas energy imbalance is associated with many diseases (i.e., obesity, diabetes, cardiovascular disease). Circadian clock is the main regulator of metabolism, and this analysis provides an overview of the bidirectional effect of circadian rhythm on metabolic processes and energy balance.Summary: The circ...
Source: Annals of Nutrition and Metabolism - Category: Nutrition Source Type: research
Background: Health risks associated with the high consumption of sugar-sweetened beverages (SSBs) include overweight or obesity and their complications such as diabetes, as well as oral and dental decay, among others.Aim: The aim of the present statement is to inform health care professionals, parents, care-givers, teachers and school head teachers, stakeholders and governing bodies about the risks associated with drinking SSBs in infants, children and adolescents.Methods: We searched PubMed and the Cochrane databases for English language studies published from 2010 through October 1, 2018, for randomized clinical trials, ...
Source: Annals of Nutrition and Metabolism - Category: Nutrition Source Type: research
Authors: Tayal R, Hirst CS, Garg A, Kapur NK Abstract INTRODUCTION: Use of acute mechanical circulatory support (MCS) devices for high-risk cardiac intervention, cardiogenic shock, and advanced heart failure is growing. Alternate vascular access options for these devices remains a clinical challenge. Building on experience from trans-aortic valve replacement procedures, the axillary artery is becoming a common access route for acute MCS and represents an important advance in the development of acute MCS technologies. Areas covered: Authors review the clinical data and technical aspect of acute MCS deployment via th...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
The objective of this study was to investigate the frequency of symptoms related to comorbid neurodevelopmental disorders, the autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in children with typical BECTS, and to identify corresponding risk factors.MethodsChildren and adolescents with typical BECTS aged 6–16 years were included in the study period from January 1, 2017, to December 31, 2017. Children with atypical presentations of BECTS, other neurological disorders, and preexisting neuropsychiatric disorders were excluded. The ASD and ADHD were assessed by the Social Communicatio...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
ConclusionsMost of the HBsAg-positive pregnant women (75%) did not have prophylactic information in the charts, and almost 50% of the pregnant women and newborns who had appropriate prophylaxis did not return for medical follow-up. Failure of prophylaxis can promote vertical/perinatal transmission of hepatitis B virus in newborns of mothers who are HBsAg positive.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
(NEW YORK) — U.S. measles cases in 2019 have climbed to their highest level in 25 years in a resurgence largely attributed to misinformation that is turning parents against vaccines. New York City health officials on Wednesday reported 61 new cases since late last week, pushing this year’s nationwide tally past the 667 cases reported for all of 2014. That would make 2019 the worst year for measles since 1994. The Centers for Disease Control and Prevention updates its national measles count on Mondays. CDC officials said they are reviewing the latest reports. Roughly three-quarters of this year’s illnesses...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized measles onetime Source Type: news
Most states have statutes that invalidate a woman's advance directive if she is pregnant, a U.S. study finds. And because those statutes are often not clearly outlined in the DNR form, women filling out an advance directive most likely would not know that it wouldn't apply if they were pregnant, researchers reported Tuesday online in JAMA.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
CONCLUSIONS: Shoulder pain may associated with obesity and we recommend the addition of weight control to the treatment of patients with shoulder pain. PMID: 31006662 [PubMed - as supplied by publisher]
Source: Journal of Back and Musculoskeletal Rehabilitation - Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research
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