Memantine for Prophylactic Treatment of Migraine Without Aura: A Randomized Double‐Blind Placebo‐Controlled Study

ConclusionMemantine might be a tolerable and efficacious option for prophylaxis in patients with migraine without aura. Tolerability, short duration required for titration, and safety profile in pregnancy might give memantine an advantage over other antimigraine medications. The study was registered in the Iranian Registry of Clinical Trials (Registration number: IRCT2013120115616N1).

Source: Headache: The Journal of Head and Face Pain - December 6, 2015 Category: Neurology Authors: Rezvan Noruzzadeh, Amirhossein Modabbernia, Vajiheh Aghamollaii, Majid Ghaffarpour, Mohammad Hossein Harirchian, Sarvenaz Salahi, Nikta Nikbakht, Nahid Noruzi, Abbas Tafakhori Tags: Research Submissions Source Type: research