Identifying Potential Breast Carcinogens: A New Approach

This study could help to bridge that gap by proposing an intriguing and novel screening strategy for breast cancer carcinogens,” Guyton says. There is evidence that both genotoxic and nongenotoxic mechanisms drive the development and growth of breast cancer—a consideration that is built into the HIA-BC framework. And although this testing scheme focuses on breast cancer, the authors say the same approach could be used to develop hazard assessment schemes relevant to other diseases as well. “We really have the chance, by improving the way we’re testing chemicals, to detect those that are setting us up for future disease,” says lead author Megan Schwarzman, a physician and environmental health researcher at UC Berkeley. “I’m eager to see the work continue, and continue relative to other diseases, so it can enrich the chemical testing being done on the national level.” References 1. National Research Council. Toxicity Testing in the 21st Century: A Vision and a Strategy. Washington, DC:National Academies Press (2007); Available: http://www.nap.edu/catalog/11970/toxicit​y-testing-in-the-21st-century-a-vision-a​nd-a [accessed 9 November 2015]. 2. Schwarzman MR, et al. Screening for chemical contributions to breast cancer risk: a case study for chemical safety evaluation. Environ Health Perspect 123(12):1255–1264 (2015); doi: 10.1289/ehp.1408337. 3. BCCP. Breast Cancer and Chemicals Policy Project [website]. Berkeley, CA:Breast Cancer and Chemicals Policy, Ce...
Source: EHP Research - Category: Environmental Health Authors: Tags: Featured News Science Selection December 2015 Source Type: research