New Vaccines for Head and Neck Cancer Therapy
ICT has developed a new vaccine for patients with head and neck cancer. The vaccine is designed to induce a powerful immune response against cancer cells that remain in patients who have completed conventional therapy. The vaccine is designed as an adjunct, not a replacement, to conventional cancer treatments.
CONCLUSION: This review has provided an overview of the scope of rehabilitation interventions available for survivors of head and neck cancer and preliminary information about their efficacy. This is foundational information for the development and refinement of rehabilitation interventions and programs for head and neck cancer survivors. Implications for Rehabilitation The existing evidence suggests that survivors of head and neck cancer can benefit from early screening of potential rehabilitation needs and being involved in preventive rehabilitation programs pre-surgery when possible. Rehabilitation programs should consi...
AbstractPurposeThe purpose of this study was to examine the relationship between physical impairments, quality of life and disability in patients following neck dissection, with consideration of patient and clinical characteristics.MethodsCross-sectional study of patients
The Global Burden of Disease (GBD) project provides longitudinal analysis of the global burden of otolaryngologic diseases by measuring the all-cause mortality, years of life lost, the years of life lived with disability, and disability-adjusted life years. Hearing loss burden is assessed overall and as sequelae of other diseases, such as otitis media or meningitis. Using these measures, we can appreciate the high prevalence and disability related to hearing loss globally. Other otolaryngologic diseases that contribute to the GBD include otitis media, cleft lip and palate, head and neck cancer, facial trauma, and oral disorders.
Head and neck cancer (HNC) is one of the most common malignancies worldwide . In patients with advanced HNC, the standard of care often involves radical resection, chemotherapy, and radiotherapy . Multidisciplinary treatments invariably cause mucositis, xerostomia, and odynophagia, resulting in swallowing disabilities. In addition, severe malnourishment may interrupt treatment or even cause death. Poor nutritional status increases radiation-induced toxicity and is associated with poor clinical outcome .
Conclusion: The results of the present study suggest very low shoulder morbidity in patients after SCAIF procedure with no significant functional impairment of the donor shoulder compared with the contralateral side.
In this study, the effect of radiotherapy (RT) on hearing function of patients with head and neck cancer after RT was determined according to the total dose delivered to specific parts of the auditory system. A total of 66 patients treated with primary or postoperative radiation therapy for various cancers in the head and neck region were selected. All patients had audiologic evaluation with pure tone audiometry for the frequencies of 250, 500, 1,000, 2,000, 3,000, 4,000, 6,000, and 8,000 Hz before and immediately after completion of treatment and again 3 months later. The cochlea dose volume histograms of the patients wer...
ConclusionThis is the first study to demonstrate a high prevalence of poor sleep quality in long-term head and neck cancer survivors. Extensive neck dissection, poor mental health, and psychological disability may contribute to poor sleep quality. Maintaining good oral health-related quality of life could promote better sleep in these patients.
More than 500,000 cases are diagnosed as head and neck cancer (HNC) annually worldwide [1,2]. In Taiwan, HNC is one of the top five increasing cancers over the past decade and the fifth most common cancer . More than half of the patients with HNC survive more than 5 â€¯years , but this is accompanied by treatment-related complications and subsequent profound disability . HNC treatments, including surgical dissection, chemotherapy, and radiation therapy, contribute to complications involving shoulder dysfunction, pain in the upper extremities, and physical inactivity [6–9].
To estimate the clinical burden of head and neck cancer (HNC) to the Brazilian society through the calculation of disability-adjusted life years (DALY).
Conclusions: We propose that the inhibition of chromatin assembly represents a novel mechanism of cell transformation induced by the environmental and occupational chemical carcinogen FA. https://doi.org/10.1289/EHP1275 Received: 25 October 2016 Revised: 19 May 2017 Accepted: 23 May 2017 Published: 21 September 2017 Address correspondence to C. Jin, Dept. of Environmental Medicine, New York University School of Medicine, 57 Old Forge Rd., Tuxedo Park, NY 10987 USA. Telephone: (845) 731-3602. Email: Chunyuan.email@example.com *Current affiliation: Medical School of Nanjing University, Nanjing, China. †Current affil...