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New Vaccines for Head and Neck Cancer Therapy

ICT has developed a new vaccine for patients with head and neck cancer. The vaccine is designed to induce a powerful immune response against cancer cells that remain in patients who have completed conventional therapy. The vaccine is designed as an adjunct, not a replacement, to conventional cancer treatments.
Source: Disabled World - Category: Disability Tags: Treatments Source Type: news

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AbstractPurposeThe purpose of this study was to examine the relationship between physical impairments, quality of life and disability in patients following neck dissection, with consideration of patient and clinical characteristics.MethodsCross-sectional study of patients
Source: Journal of Cancer Survivorship - Category: Cancer & Oncology Source Type: research
The Global Burden of Disease (GBD) project provides longitudinal analysis of the global burden of otolaryngologic diseases by measuring the all-cause mortality, years of life lost, the years of life lived with disability, and disability-adjusted life years. Hearing loss burden is assessed overall and as sequelae of other diseases, such as otitis media or meningitis. Using these measures, we can appreciate the high prevalence and disability related to hearing loss globally. Other otolaryngologic diseases that contribute to the GBD include otitis media, cleft lip and palate, head and neck cancer, facial trauma, and oral disorders.
Source: Otolaryngologic clinics of North America - Category: ENT & OMF Authors: Source Type: research
Conclusion: The results of the present study suggest very low shoulder morbidity in patients after SCAIF procedure with no significant functional impairment of the donor shoulder compared with the contralateral side.
Source: Plastic and Reconstructive Surgery – Global Open - Category: Cosmetic Surgery Tags: Original Article Source Type: research
In this study, the effect of radiotherapy (RT) on hearing function of patients with head and neck cancer after RT was determined according to the total dose delivered to specific parts of the auditory system. A total of 66 patients treated with primary or postoperative radiation therapy for various cancers in the head and neck region were selected. All patients had audiologic evaluation with pure tone audiometry for the frequencies of 250, 500, 1,000, 2,000, 3,000, 4,000, 6,000, and 8,000 Hz before and immediately after completion of treatment and again 3 months later. The cochlea dose volume histograms of the patients wer...
Source: Ear, Nose and Throat Journal - Category: ENT & OMF Authors: Tags: Ear Nose Throat J Source Type: research
ConclusionThis is the first study to demonstrate a high prevalence of poor sleep quality in long-term head and neck cancer survivors. Extensive neck dissection, poor mental health, and psychological disability may contribute to poor sleep quality. Maintaining good oral health-related quality of life could promote better sleep in these patients.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
More than 500,000 cases are diagnosed as head and neck cancer (HNC) annually worldwide [1,2]. In Taiwan, HNC is one of the top five increasing cancers over the past decade and the fifth most common cancer [3]. More than half of the patients with HNC survive more than 5  years [4], but this is accompanied by treatment-related complications and subsequent profound disability [5]. HNC treatments, including surgical dissection, chemotherapy, and radiation therapy, contribute to complications involving shoulder dysfunction, pain in the upper extremities, and physical inactivity [6–9].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research
To estimate the clinical burden of head and neck cancer (HNC) to the Brazilian society through the calculation of disability-adjusted life years (DALY).
Source: Value in Health - Category: International Medicine & Public Health Authors: Source Type: research
Conclusions: We propose that the inhibition of chromatin assembly represents a novel mechanism of cell transformation induced by the environmental and occupational chemical carcinogen FA. https://doi.org/10.1289/EHP1275 Received: 25 October 2016 Revised: 19 May 2017 Accepted: 23 May 2017 Published: 21 September 2017 Address correspondence to C. Jin, Dept. of Environmental Medicine, New York University School of Medicine, 57 Old Forge Rd., Tuxedo Park, NY 10987 USA. Telephone: (845) 731-3602. Email: Chunyuan.jin@nyumc.org *Current affiliation: Medical School of Nanjing University, Nanjing, China. †Current affil...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Treatment TermsSkull base tumor Author Karen Doss Bowman Overview Victoria Vesce had surgery and 28 rounds of radiation for rare tumors in the base of her skull and in her neck. Four days after her last radiation treatment, she started law school. Hero Image20170809.vesce_.victoria.03.blog_.jpg Preview Image Content Blocks Section Header Image/Videovesce_honeybee_blog.jpg Section Features Images/Media Text Content Section Header Image/Videovesce_blog_secondary3.jpg Section Features Images/Media Text Content Header A Regional Destination for Rare Head and Neck Tumors ContentPatients from throughout the Sou...
Source: dukehealth.org: Duke Health News - Category: Consumer Health News Authors: Source Type: news
Conclusion The CHI showed acceptable psychometric qualities and can be considered as an authentic clinical tool for health professionals, assessing the impact of ENT pathology on quality of life, mainly in the functional domains directly affected by the pathology or treatment.
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
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