ADHD Study: Reducing the Need for High Medication Doses with Behavior Therapy

Medication treatment and behavior therapy are both considered effective treatments for ADHD; the combination of these treatments is generally regarded as an ideal approach for many children. However, in the Multimodal Treatment Study of ADHD (MTA Study), the largest ADHD treatment study ever conducted, the benefit of combined treatment relative to medication treatment alone — while significant for some outcome measures — was not especially robust. This has led some professionals to question whether behavior therapy is necessary when a child is being effectively treated with medication, i.e., will behavior therapy make a sufficient different to be worthwhile? (For a review of the initial set of findings from the MTA study. One limitation of most prior studies examining combined treatment — MTA included — is that the incremental benefits of behavior therapy have been examined in the context of an optimized medication dose. For example, each child in the MTA Study began medication treatment with an intensive placebo-controlled trial to determine his or her most effective dose. Thus, the benefits of adding behavioral treatment to medication was evaluated in the context of an optimized medication regime. Generally speaking, the incremental benefits of behavior treatment when evaluated in this context are modest at best. However, medication treatment in community settings is rarely delivered in ways to optimize benefits. And, an entirely different but import...
Source: SharpBrains - Category: Neurologists Authors: Tags: Attention and ADD/ADHD Cognitive Neuroscience behavior-therapy medication Source Type: blogs

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Condition:   ADHD Predominantly Inattentive Type Interventions:   Behavioral: Cognitive-behavioral therapy (Hesslinger protocol);   Behavioral: Cognitive-behavioral therapy (CADDI protocol) Sponsor:   Karolinska Institutet Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In this study, we evaluated dose-dependent effects of d-amphetamine and atomoxetine on probabilistic discounting of Lewis and F344. Male Lewis and F344 chose between one food pellet delivered 100% of the time and three food pellets delivered following decreasing probabilities of delivery (i.e. 100%, 66.7%, 33.3%, 16.5%, and 8.25%). Saline, d-amphetamine (0.1–1.8 mg/kg), and atomoxetine (0.1–7.8 mg/kg) were tested acutely. Lewis and F344 did not differ in choice at baseline. d-Amphetamine increased risky choice for both rat strains at low-to-moderate doses, although it did so at a lower dose (0.1 and 0.3 mg/kg) ...
Source: Behavioural Pharmacology - Category: Drugs & Pharmacology Tags: Research Reports Source Type: research
Let’s dive into this week’s Psychology Around the Net for some perspective on how we decide to trust the news we trust, new research on a hormone we secrete when we’re panicked, a survey that shows happy people don’t just ignore the social issues around them, and more. Substance Use in the Food Service Industry: The American Addiction Centers recently conducted a survey that sheds some light on substance use among workers in the food service industry, an industry that is often stereotyped for drug and alcohol use. Among some of the findings: 10% of workers report they work while under the influence...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Psychology Around the Net Adhd food service Forgetfulness Happiness Hormones Inattention osteocalcin Pollyanna hypothesis sexism Social Issues Stress Substance Use women Source Type: blogs
Products made with CBD — touted as a cure-all for everything from insomnia to epilepsy, from arthritis to ADHD — are seemingly everywhere we look. Here's why you should discuss it with your doctor.
Source: L.A. Times - Health - Category: Consumer Health News Source Type: news
ConclusionsThe results suggest that neuropsychological underperformance associated with OCD and ADHD may be related to the presence of comorbid disorders, such as depression, rather than disorder-specific phenomena, highlighting the importance of excluding participants with comorbid disorders in neuropsychological studies and targeting comorbidities in clinical contexts.
Source: Journal of Obsessive Compulsive and Related Disorders - Category: Psychiatry Source Type: research
CONCLUSION: Youth with headache exert a considerable economic burden on families, healthcare systems, and society. Due to the limitations in methods used to classify youth with headache in MEPS, our findings may underestimate the true prevalence and cost of pediatric headache in the United States. Further research with larger sample sizes is needed to understand the impact of psychiatric comorbidities on healthcare expenditures in this population. PMID: 31520418 [PubMed - as supplied by publisher]
Source: Headache - Category: Neurology Authors: Tags: Headache Source Type: research
Conclusion: The results suggest that by optimization of variables such as solution concentration of MDF-ERS nanofibers and nanobeads with higher dissolution rates can be made by electrospray. Electrospray deposition as a simple, continuous, and surfactant free method is an excellent choice for preparation of drug loaded polymeric nanoparticles. PMID: 31508333 [PubMed]
Source: BioImpacts - Category: Research Tags: Bioimpacts Source Type: research
CONCLUSION: Prenatal exposure to acetaminophen was associated with an increased risk of ADHD in offspring, regardless of gestational infections and maternal mental health disorders. Additional studies are necessary to clarify the underlying mechanisms by which prenatal exposure to acetaminophen leads to neurodevelopmental risks. PMID: 31509360 [PubMed - in process]
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
This study used data from the Millennium Cohort Study to investigate the relationship between NOSI and emotional symptoms, conduct problems, and hyperactivity/inattention as assessed by the Strengths and Difficulties Questionnaire (SDQ) in 1,280 youths, aged 14 years. Furthermore, the relationship between NOSI and decision-making processes as assessed by the Cambridge Gambling Task (CGT) was investigated. Hyperactivity/inattention and conduct problems were significantly associated with NOSI; emotional problems were not. Risk taking was significantly associated with misbehaving in lessons but not with being rude or noisy in...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion: This study demonstrates that SRE of MDP to alleviate symptoms of a range of mental or physiological diagnoses is higher compared to conventionally offered treatment options, and lower than regular (‘full’) psychedelic doses. Future RCTs in patient populations should objectively assess the effectivity claims of psychedelics, and whether these are dose related, disorder specific, and superior to conventional treatments.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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