What are the Most Common Arboviruses in Children in the US?

Discussion Arboviruses are viruses transmitted by arthropods (primarily mosquitos and ticks) to humans. Most infections are asymptomatic. Many others have mild symptoms such as an influenza-like illnesses. But for some patients they can cause neuroinvasive disease with meningitis, encephalitis and flaccid paralysis. Some patients also unfortunately die. Diagnosis is by serum or cerebrospinal fluid IgM antibody to the specific virus. Treatment is supportive only as there is no specific treatment and currently there are no vaccines for prevention. Mosquito bite and tick bite prevention are the best options for families and can be reviewed here. A systematic review of West Nile Virus (WNV) neuroinvasive disease in adults showed those infected can have a lengthy recovery with many sequelae, particularly muscle weakness, fatigue, myalgia and headache commonly along with memory loss, depression and concentrating difficulty. Common arbovirus characteristics include: West Nile Virus Flavivirus Transmitted by Culex mosquito with birds as reservoir Seen in areas of Africa (originally identified in 1937 in Uganda in the West Nile District), Europe, the Middle East, North America and West Asia Has spread to most states in the United States and many Canadian provinces and is the most common reported arbovirus in children Older children and teenagers seem to be more common Incubation period usually 2-6 days, but 2-14 days is possible 70-80% asymptomatic, 20% influenza like illness (i.e...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news

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Enterovirus A71 (EV-A71) receptors that have been identified to date cannot fully explain the pathogenesis of EV-A71, which is an important global cause of hand, foot, and mouth disease and life-threatening encephalitis. We identified an IFN-γ–inducible EV-A71 cellular entry factor, human tryptophanyl-tRNA synthetase (hWARS), using genome-wide RNAi library screening. The importance of hWARS in mediating virus entry and infectivity was confirmed by virus attachment, in vitro pulldown, antibody/antigen blocking, and CRISPR/Cas9-mediated deletion. Hyperexpression and plasma membrane translocation of hWARS were obs...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
A child from Florida is the first person to die of the flu this season. The child was unvaccinated with no known underlying medical conditions. But a new survey shows more parents don't see the benefits of the flu vaccine. CBS News medical contributor Dr. Tara Narula has more.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
One in four Americans goes to a therapist, and CBT is the most popular and safest treatment for depression. But 43 percent experience anxiety, break ups or other side effects, a German study reveals.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
More than half of Americans who suffer from depression never get any treatment, and in many cases that ’s because their symptoms are never diagnosed. The U.S. Preventive Services Task Forceadvises primary care physicians to screen all of their patients for depression and make sure proper care gets...
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news
BOSTON (CBS) – As we head into the heart of flu season, Dr. Mallika Marshall provides the facts you need to know to keep you and your family safe. The time to get vaccinated against the flu is now. The vaccine is widely available at doctor’s offices and pharmacies and it take a couple of weeks to build immunity to the flu and the flu season has started. Massachusetts has seen at least 80 lab-confirmed cases of influenza so far, which is typical for this time of year. Plus, a child in Florida has already died from the flu. She was healthy but had not been vaccinated. Getting the flu shot is the best way to prote...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Seen On WBZ-TV Syndicated Local Watch Listen Dr. Mallika Marshall Flu Flu Vaccine Source Type: news
Sarah Bradshaw, from Hampshire, long suffered with depression and anxiety. But the mother-of-three undertook repetitive transcranial magnetic stimulation therapy - and it changed her life.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionsThe findings suggest that the stigma associated with parenting a child with disabilities may be one mechanism that places such parents at risk for poor health. Efforts to alleviate the stigma associated with developmental disorders or mental health problems may have beneficial effects on health of parents of individuals with such conditions.
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
A child in Florida who wasn't vaccinated has died from getting the flu.
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Following a difficult surgery, some patients end up experiencing cognitive decline and delirium, which seems to arise from inflammatory changes in the brain, that are still poorly understood. This inflammation is difficult to control in a targeted wa...
Source: Medgadget - Category: Medical Devices Authors: Tags: Genetics Medicine Neurology Pain Management Source Type: blogs
ConclusionsPCOS is associated with an increased risk of diagnosis of depression, anxiety, bipolar disorder, and obsessive compulsive disorder. It is associated with worse symptoms of depression, anxiety, OCD, and somatization. Screening for these disorders to allow early intervention may be warranted.
Source: Endocrine - Category: Endocrinology Source Type: research
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