What are the Most Common Arboviruses in Children in the US?
Discussion Arboviruses are viruses transmitted by arthropods (primarily mosquitos and ticks) to humans. Most infections are asymptomatic. Many others have mild symptoms such as an influenza-like illnesses. But for some patients they can cause neuroinvasive disease with meningitis, encephalitis and flaccid paralysis. Some patients also unfortunately die. Diagnosis is by serum or cerebrospinal fluid IgM antibody to the specific virus. Treatment is supportive only as there is no specific treatment and currently there are no vaccines for prevention. Mosquito bite and tick bite prevention are the best options for families and can be reviewed here. A systematic review of West Nile Virus (WNV) neuroinvasive disease in adults showed those infected can have a lengthy recovery with many sequelae, particularly muscle weakness, fatigue, myalgia and headache commonly along with memory loss, depression and concentrating difficulty. Common arbovirus characteristics include: West Nile Virus Flavivirus Transmitted by Culex mosquito with birds as reservoir Seen in areas of Africa (originally identified in 1937 in Uganda in the West Nile District), Europe, the Middle East, North America and West Asia Has spread to most states in the United States and many Canadian provinces and is the most common reported arbovirus in children Older children and teenagers seem to be more common Incubation period usually 2-6 days, but 2-14 days is possible 70-80% asymptomatic, 20% influenza like illness (i.e...
Authors: Ibrahim E, Sultan W, Helal S, Abo-Elwafa H, Abdelaziz A Abstract BACKGROUND: Conscious sedation is usually required during flexible bronchoscopy. Sedation should be achieved without respiratory depression or loss of consciousness. The present study was designed to evaluate the effect of pregabalin pre-medication on reducing the amount of sedatives and to show its advantages for patients undergoing flexible bronchoscopy with dexmedetomidine. METHODS: Seventy patients undergoing elective flexible bronchoscopy were randomly divided into two groups of 35 patients each. All patients received premedication o...
Authors: Wirz-Justice A, Ajdacic V, Rössler W, Steinhausen HC, Angst J Abstract The prevalence of autumn/winter seasonality in depression has been documented in the longitudinal Zurich cohort study by five comprehensive diagnostic interviews at intervals over more than 20 years (N = 499). Repeated winter major depressive episodes (MDE-unipolar + bipolar) showed a prevalence of 3.44% (5× more women than men), whereas MDE with a single winter episode was much higher (9.96%). A total of 7.52% suffered from autumn/winter seasonality in major and minor depressive mood states. ...
CONCLUSIONS: These findings correspond with the idea that mindfulness reduces incongruencies between implicit and explicit emotional responses. We found preliminary evidence for this effect for negative emotional responses. There was suggestive evidence that congruence arose from the alignment of explicit responses (which became less stable) to implicit responses (which remained stable). Studying the interplay between implicit and explicit processes may shed light on the working mechanisms of clinical-psychological interventions. PMID: 30022567 [PubMed - as supplied by publisher]
ConclusionDiagnostic accuracy of FLAIR in detection of acute subarachnoid hemorrhage in patients presenting with severe headache taking lumbar puncture as gold standard is higher and reliable.
Authors: Rizo CF, Wretman CJ, Macy RJ, Guo S, Ermentrout DM Abstract Female intimate partner violence (IPV) survivors who are their children's primary caregivers are often mandated to services by child protection services (CPS) and/or the courts. Unfortunately, scant evidence exists regarding mandated programs for CPS- and/or court-involved IPV survivors, particularly the mental health outcomes of such programs. Two human service agencies in the southeastern United States collaborated to develop and implement a novel 13-week intervention to address the needs of these mothers' as related to safety, parenting, and me...
Abstract: Lyme disease is the most commonly reported vector-borne disease in the United States. After initial antibiotic treatment for patients with Lyme disease, ongoing symptoms that may persist have considerable long-term impact on healthcare costs. Posttreatment Lyme disease syndrome is characterized by a host of chronic symptoms that can leave patients physically and mentally disabled.
Abstract: Patients with diabetes are sometimes overwhelmed with the burden of self-care associated with the disease. Although it may seem appropriate to diagnose patients experiencing such emotional burdens with depression, the literature over the past 20 years has matured the concept of diabetes distress, which may more accurately describe the phenomenon.
Publication date: Available online 20 July 2018Source: The LancetAuthor(s): Laurie Garrett
CONCLUSION: This study reported high rates of HBV markers of infection among SCD patients. It is therefore advocated that donated blood must pass through rigorous screening processes before it is transfused. PMID: 30024816 [PubMed - as supplied by publisher]
ConclusionsCeftazidime-avibactam may be a valuable option for serious infections due to resistant P. aeruginosa.
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