A label-free electrochemical aptasensor for the analysis of the potassium ion.

A label-free electrochemical aptasensor for the analysis of the potassium ion.
J Immunoassay Immunochem. 2015;36(2):162-9
Authors: Ji X, Li J, Yang C
Abstract
Herein, a simple and novel electrochemical method for the detection of potassium ions (K(+)) was developed. In the presence of potassium ions, the potassium ions aptamer will form a G-quadruplex complex. Thus, further addition of hemin in the presence of potassium ions will lead to the formation of a recombined G-quadruplex. Then the electroactive label, hemin, will give an electrochemical response. The linear range of the method covered a large variation of K(+) concentration from 0.1 nM to 0.1 μ M and the detection limit of 0.1 nM was obtained. Moreover, this assay was able to detect K(+) with high selectivity and had great potential applications.
PMID: 24785341 [PubMed - indexed for MEDLINE]

Source: Journal of Immunoassay and Immunochemistry - November 29, 2015 Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research